The hemostatic effect of calcium alginate in experimental splenic injury model
Yükleniyor...
Dosyalar
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Assoc Trauma Emergency Surgery
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
BACKGROUND We evaluated the effect of calcium alginate as a hemostatic agent in a splenic injury model. METHODS Experimental rats (Wistar albino) were divided into four groups. Group I: Laparotomy was not performed. Group II: After laparotomy, the abdomen was closed without any splenic injury. Group III: After laparotomy, splenic injury about 0.5 cm in depth and 0.3 cm in length was created by standard Rochester pean forceps. Physiological serum treated gauze dressing, about 2x2 cm in size, was applied to the injured splenic tissue for 3 minutes. Group IV: After laparotomy, standard splenic injury about 0.5 cm in length and 0.3 cm in depth was created. Calcium alginate wound dressing, 1x1 cm in size, was applied to the splenic wound. In all groups, blood samples for bleeding time and hemogram were taken. Peroperative blood loss, pre- and post-operative hemoglobin and hematocrit values were calculated. RESULTS Comparing hematocrit values and peroperative bleeding in Groups III and IV, Group IV had a lower decline in hematocrit values and lower peroperative bleeding. CONCLUSION Calcium alginate has hemostatic capacity. It may be used in splenic injuries, especially for Grades I and II.
Açıklama
Ankarali, Seyit/0000-0003-3752-0846
WOS: 000319368700002
PubMed: 23720104
WOS: 000319368700002
PubMed: 23720104
Anahtar Kelimeler
Calcium alginate, hemostasis, splenic injury
Kaynak
Ulusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal Of Trauma & Emergency Surgery
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
19
Sayı
3
