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https://hdl.handle.net/20.500.12684/4

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Early Motor Repertoire and Developmental Functioning at Later Age of Children Who Were Diagnosed with Autism Spectrum Disorder: A Pilot Study
(Taylor & Francis, 2025) Kınacı-Biber, Esra; Yardımcı-Lokmanoğlu, B.N.; Mutlu, A.
Aims: Autism Spectrum Disorder (ASD) may exhibit early motordelay, and long-term motor impairments in addition to social andcommunicative problems. This pilot study aimed to describe (i) theearly motor repertoire using General Movements Assessment (GMA)of infants later diagnosed with ASD, (ii) the developmental outcomesin these children between 24- and 42-months, and (iii) the relation-ship between GMA and developmental outcomes.Methods: Ten children diagnosed with ASD were included. Allinfants were assessed using Motor Optimality Score for 3- to 5-month-old Infants–Revised score sheet for GMA, and the BayleyScales of Infant and Toddler Development, Third Edition (Bayley-III)for developmental functioning aged between 24- and 42-months.Results: The median Motor Optimality Score-Revised (MOS-R) was 10(range: 6–28), considered reduced optimal, and 80% of children hadless than optimal MOS-R. 60% of the children had aberrant fidgetymovements and abnormal postural patterns, and 80% had abnormalbut not cramped-synchronized movement character. The mean com-posite scores of all subdomains in Bayley-III were below 69(extremely low) in all children.Conclusions: This study highlighted the importance of early motorrepertoire and longitudinal developmental assessments in childrenwith ASD. Further research is needed to explore the potential of thisassessment as a screening tool.
Investigation of Gait Characteristics and Kinematic Deviations in Rare Genetic Disorders with Instrumented Gait Analysis. Journal of Intellectual Disability Research, 69(5), 383-392.
(Wiley, 2025) Kınacı-Biber, Esra; Gys, L.; Jansen, A. C.; Schoonjans, A. S.; Van Dijck, A.; Kooy, R. F.; Hallemans, A. (2025).
Background: Dravet Syndrome (DS), Helsmoortel-Van Der Aa Syndrome (HVDAS) and Tuberous Sclerosis Complex (TSC)are rare genetic syndromes, sharing intellectual disability (ID) and motor delay. In DS, two distinct gait patterns, crouch andnon-crouch, have been described using instrumented 3D gait analysis (i3DGA). This cross-sectional study measures gait in par-ticipants with TSC and HVDAS. The findings are compared to the known crouch and non-crouch gait patterns observed in DSand to typical gait.Methods: Participants (6–22 years) with DS (n = 37; 19 crouch and 18 non-crouch), HVDAS (n = 12) or TSC (n = 8) were comparedwith typically developing (TD) peers (n = 33). All participants underwent i3DGA (Plugin Gait model processed with Vicon Nexusand MATLAB®) to investigate spatiotemporal and lower-limb kinematics.Results: All three genetic syndromes showed increased step width. Participants with HVDAS and DS, but not participants withTSC walked with decreased step length and velocity compared to TD. HVDAS demonstrated increased knee flexion during thestance phase, lack of hip extension during pre-swing, and increased ankle dorsiflexion during some phases of the gait cycle(p < 0.001). Additionally, HVDAS showed similar kinematic deviations to DS-NonCrouch. No significant differences were foundin terms of kinematics between TSC and TD peers (p > 0.05).Conclusion: The current study reveals differences in gait characteristics from typical functional gait in rare genetic disorders.DS- Crouch, DS-NonCrouch and HVDAS display a more impaired gait from a biomechanical perspective than TSC. The variabil-ity of clinical and genetic features might explain heterogeneity in gait deviations and should be further explored.
Effects of kinesiotaping combined with physical therapy in patients with migraine-associated neck pain: a randomized controlled study
(Springer Nature, 2025) Kınacı-Biber, Esra; Polat, B.
Background To investigate the effects of kinesiotaping (KT) combined with physical therapy (PT) on pain severity and frequency, pressure pain threshold (PPT), disability, and quality of life (QoL) in migraine patients with neck pain, in addition to pharmacologic treatment. Methods Sixty patients with migraine were randomly allocated to the three groups and received PT for 6 weeks (12 sessions, including cervical exercises and mobilizations): treatment group (TG; n = 20), placebo group (PG; n = 20), and control group (CG; n = 20). KT in TG and sham taping in PG were administered during each session. Headache frequency, pain severity (VAS-headache, VAS-neck pain), PPT, neck disability, and QoL were evaluated at baseline and posttreatment. Results The TG showed a clinically significant improvement in headache intensity (?2 = 0.432, p = 0.003), neck pain severity (?2 = 0.437, p < 0.001), and neck disability (?2 = 0.427, p = 0.005). Additionally, there was a significant increase in PPT for the trapezius and sternocleidomastoid muscles (p < 0.05). However, there were no significant differences between the groups in terms of headache frequency. Improvements were also observed in bodily pain and general health in QoL (p < 0.05). Conclusion The findings suggest that KT combined with PT and pharmacological treatment significantly improves clinical outcomes in migraineurs with neck pain. Specifically, the TG demonstrated greater reductions in intensity of headache and neck pain, along with increases in PPT and improvements in disability and QoL compared to both groups. These results can support the potential effectiveness of a combined treatment approach targeting both cervical musculoskeletal dysfunction and migraine symptoms. Nevertheless, further studies with longer follow-up periods are required to confirm of these benefits.
Muscle Thickness in Lower Extremity and LocomotorFunctions in Children With Down Syndrome and TypicalDeveloping Peers
(Wiley, 2026) Kınacı-Biber, Esra; Soylu, A. R.; Topuz, S.; Mutlu, A.
Objectives Children with Down syndrome (DS) have deficits in motor skills that lead to stereotypical changes in the characteristics and adaptations of their movement. The aim of the study was to investigate locomotor characteristics and muscle thickness of the selected muscles in the lower extremity and the relationship between muscle thickness and locomotor parameters in children with DS and typically developing peers. Methods Children with DS (n?=?18; age: 5.36?±?0.60) and typically developing (TD) (n?=?30; age: 5.62?±?0.60) aged 4–7?years participated. Lower limb muscle thickness was assessed through B-mode ultrasound. The GAITRite system evaluated gait and running spatiotemporal parameters, using linear regression to determine the strength of the relationship between muscle thickness and these parameters. Results Compared to the TD group, the DS group had significantly less lower limb muscle thickness and differed significantly in gait and running parameters (p?
A Schur Type Theorem For Almost Cosymplectic Manifolds With Kaehlerian Leaves.
(2013) Aktan, N.; Ayar, Gülhan; Bektas, I.
In this study, we give a Schur type theorem for almost cosymplectic manifolds with Keahlerian leaves.
Geometry of Kenmotsu Manifolds via Q-Curvature Tensor and Schouten–Van Kampen Connection.
(2025) Yıldırım, M.; Beyendi, S.; Ayar, Gülhan; Aktan, N.
This research paper aims to study the Q-curvature tensor on Kenmotsu manifolds endowed with the Schouten–van Kampen connection. Using the Q-curvature tensor, whose trace is the well-known Z-tensor, we characterized Kenmotsu manifolds by introducing the notion of ?-Q flat and ?-Q flat manifolds and novel tensor conditions, such as Q(?,X)Q=0, Q(?X)R=0, Q(?,X)S=0, Q(?,X)C=0 ,Q(?,X)H=0, and Q(?,X)P=0, with the Schouten–van Kampen connection. To validate some of our results, we constructed a non-trivial example of Kenmotsu manifolds endowed with the Schouten–van Kampen connection.
A Physical Classification of Killing Magnetic Fields In Thurston Geometries.
(2024) Dündar, F S.; Kelekçi, Ö.; Ayar, Gülhan
In recent years, numerous studies have appeared that considered Killing vectors of three-dimensional Riemannian manifolds as magnetic fields, since these vector fields are divergenceless by definition. The existence of adivergenceless vector field modeled as a magnetic field does not imply that it is physically realizable. In this study, we propose a physical classification scheme based on the divergences of the integral that defines the energy of a Killing magnetic field. We consider all the Killing magnetic fields of Thurston geometries studied in the literature and classify them as either physical or nonphysical.
On a Type of ?-Cosymplectic Manifolds.
(2019) Beyendi, S. ,; Ayar, Gülhan; Aktan, N.
The ob ject of this paper is to study alpha-cosymplectic manifolds admitting a W2-curvature tensor.
Concircular Curvature Tensor of Nearly Cosymplectic Manifolds in Terms of The Generalized Tanaka-Webster Connection
(2024) Ayar, Gülhan; Aktan, N.; Madan, Ç.
In this paper, we study concircular curvature tensor of nearly cosymplectic manifolds in terms of the generalized Tanaka-Webster connection and then, we emphasized the properties that concircular curvature tensor of nearly cosymplectic manifolds in terms of the generalized Tanaka-Webster connection provides in case of flatness, ?-concircularly flatness, ?-concircularly semisymmetric.
Conharmonic Curvature Tensor on Nearly Cosymplectic Manifolds with Generalized Tanaka-Webster Connection
(2021) Ayar, Gülhan; Çavuşoğlu, H. R.
In this paper, we study conharmonic curvature tensor of nearly cosymplectic manifolds with generalized Tanaka-Webster connection and we give a conharmonically flat nearly cosymplectic manifold with respect to the connection.
Nearly Cosymplectic Manifolds wth Nullity Conditions.
(2019) Yıldırım, M.; Ayar, Gülhan
We investigate nearly cosymplectic manifolds with k-nullity distribution. Also, we consider pseudo-projectively flat N(?)-nearly cosymplectic manifold and study Ze · P = 0 condition.
New Curvature Tensors along Riemannian Submersions
(2020) Ayar, Gülhan; Akyol M. A.
In 1966, B. O’Neill [The fundamental equations of a submersion, Michigan Math. J., Volume 13, Issue 4 (1966), 459-469.] obtained some fundamental equations and curvature relations between the total space, the base space and the fibres of a submersion. In the present paper, we define new curvature tensors along Riemannian submersions such as Weyl projective curvature tensor, concircular curvature tensor, conharmonic curvature tensor, conformal curvature tensor and M?projective curvature tensor, respectively. Finally, we obtain some results in case of the total space of Riemannian submersions has umbilical fibres for any curvature tensors mentioned by the above.
Ricci Solitons and Gradient Ricci Solitons on Nearly Kenmotsu Manifold
(2019) Ayar, Gülhan; Yıldırım, M.
In this article, a number of properties have been obtained by examining Ricci solitons and gradient Ricci solitons on nearly cosymplectic manifolds.
?-Ricci Solitons on Nearly Kenmotsu Manifolds
(2019) Ayar, Gülhan; Yıldırım, M.
In this paper, we study the geometry and topology of ?-Ricci solitons satisfying Ricci semisymmetry condition, S · R = 0 condition and finally Einstein-semisymmetry condition on nearly Kenmotsu manifolds.
Pseudo-Projective and Quasi-Conformal Curvature Tensors on Riemannian Submersions.
(2021) Ayar, Gülhan
In this study, pseudo-projective and quasi-conformal curvature tensors on a Riemannian submersion have been examined and on a Riemannian submersion new curvature relations for pseudo-projective curvature tensor and quasi-conformal curvature tensor under certain conditions have been obtained.
Classification of Killing Magnetic Curves In H3
Kelekçi, Ö.; Dündar, F. S.; Ayar, Gülhan
In this paper, we study classification of magnetic curves corresponding to Killing vector fields of H3. First, we solve the geodesic equation analytically. Then we calculate the trajectories generated by all the six Killing vector fields, which are considered as magnetic field vectors, by using perturbation method up to first order with respect to the strength of the magnetic field. We present a comparison of our solution with the numerical solution for one case. We also prove that 3-dimensional (?)-Kenmotsu manifolds cannot have any magnetic vector field in the direction of their Reeb vector fields.
Analysis of Forming Limit Diagrams of DP600 Steel at Various Deformation Speeds
(2010) Uysal, Emrah; Öztürk, Fahrettin
[Abstract Not Available]
Biochemical and structural differences between C3 cotyledons and C4 leaves in species of Salsoloideae (Chenopodiaceae)
(Nature, 2025) Kocacinar, F.; Ceylan, Faik; Cömertpay, S.
C4 plants had evolved from C3 ancestors in at least more than 60 independent lineages of angiosperms, most probably in response to decreasing levels of atmospheric CO2 and environmental conditions promoting photorespiration. Salsola, Petrosimonia, and Cyathobasis genera of Salsoloideae subfamily contain some species with C3 cotyledons followed by C4 leaves. The aim of this study was to determine and compare the biochemical and structural differences between C3 cotyledons and subsequent C4 leaves in these genera. The results showed that there were isopalisade C3 cotyledons in Salsola grandis and isolateral C3 cotyledons in Cyathobasis fruticulosa, while salsoloid type C4 Kranz anatomy was present in subsequent leaves. Petrosimonia nigdeensis had dorsiventral C3 cotyledons and salsoloid-type C4 leaves. The proteins of C4 isoform phosphoenolpyruvate carboxylase (PEPC) and pyruvate orthophosphate dikinase (PPDK) enzymes were absent or very sparse in C3 cotyledons of these species, whereas they were abundant in their C4 leaves. The proteins of photorespiratory isoform glycolate oxidase (GOX) and glycine decarboxylase-H subunit (GDC-H) were generally higher in cotyledons than leaves. The protein level of photosynthetic isoform ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) enzyme was lower in C4 leaves compared to C3 cotyledons. Transcript levels of these enzymes were generally consistent with their protein content except for GOX in S. grandis and S. tragus and glycine decarboxylase complex (GDC) in S. tragus. As a result, we demonstrated that not only the protein and transcript levels of the enzymes required for C4 pathway increased, but also those levels of C3 and photorespiratory enzymes decreased during the transition from C3 cotyledons to C4 leaves. These results are considered significant in terms of shedding light on the understanding of evolutionary transition from C3 to C4 biochemical pathway in a single plant and contributing to C4 engineering.
Effects of different nitrogen doses on thymoquinone and fatty acid composition in seed oil of black cumin ( Nigella sativa L.)
(Wiley, 2022) Telci, İsa; İzgi, M. N.|Özek, T.; Yasak, Selma; Devrim, Selma; Yur, S.|Özek, G.
Black cumin, Nigella sativa L. belonging to Ranunculaceae, is a valuable medicinal plant because of the curative effects of seed and oil. Despite studies on black cumin, there are few studies on the effects of nitrogen on fatty acid composition, no records on thymoquinone yield, and the thymoquinone content of the seed oil. In this study, the effects of different nitrogen doses on the seed oil yield, thymoquinone ratio/yield, and fatty acid compositions were investigated. Field studies with nitrogen doses (0, 40, 60, 80, and 100?kg/ha) were studied using the randomized plot design. As a result of the research, nitrogen doses significantly affected the oil and thymoquinone yields while insignificant on the thymoquinone ratio. The highest oil yield with 501.6 kg/ha was obtained from 80?kg/ha of the nitrogen doses, while the highest thymoquinone yield with 10.24?kg/ha was obtained from the control plots. Thymoquinone yields were in the same statistical group with other nitrogen doses, except for means of 100?kg/ha nitrogen doses. Linoleic, oleic, and palmitic acids were major fatty acids of black cumin, and their variations were insignificant in nitrogen applications. The values of butyric, capric, and linolenic acids varied significantly in different nitrogen doses. As a result of the study, it was determined that the highest oil yield was obtained from 80?kg/ha nitrogen application. It has been determined that nitrogen doses above 60–80?kg/ha should be avoided for the seed oil and thymoquinone yields in black cumin.
Age and growth of the needlefish, Tylosurus imperialis (Rafinesque, 1810) from the Levantine coast, North-Eastern Mediterranean
(Univ Oradea Publ House, 2025) Erguden, Deniz; Turan, Cemal; Ivanova, Petya Pavlova; Dogdu, Servet Ahmet; Raykov, Violin Stoyanov; Yankova, Maria; Yaglioglu, Deniz
The present study is the first to determine the age and growth parameters of the needlefish Tylosurus imperialis in the Northeastern Mediterranean. A total of 320 specimens of T. imperialis were caught by gill nets from Turkish coasts (Iskenderun Bay) in the Northeastern Mediterranean between October 2020 and September 2021. The maximum age was 5 years for both sexes combined, and the age group 3-4 comprised 77.5 % of the samples. The total length distribution of T. imperialis was 60 to 109 cm, and the weight distribution was 309 to 1985 g. The b value was between 3.20 and 3.31 for females and males, respectively. The parameter b from the length-weight relationship characterizes a positive allometric growth. Growth equations were calculated as W=0.0006xL(3.2026) (R-2= 0.912) for females, W=0.0004xL(3.3163) (R-2= 0.896) for males, and W= 0.0005xL(3.2456) (R-2=0.904) for all specimens. Von Bertalanffy growth parameters were L-infinity= 139.29 cm, K= 0.119 year(-1), t(0)= -1.819 year for females, L-infinity= 138.50 cm, K= 0.113 year(-1), t(0)= -1.834 year for males and L-infinity= 138.33 cm, K= 0.112 year(-1), t(0)= -1.839 year for all specimens. The spawning period of T. imperialis was determined to be between April and August for both sexes. This data will be useful for the fisheries management of needlefish stocks in our study area and elsewhere.

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