The effect of vitamin D status on different neuromuscular blocker agents reverse time

Basit Öğe Kaydı
dc.authorid
dc.contributor.authorYorulmaz, İlknur
dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorÖzlü, Onur
dc.contributor.authorDost, Burhan
dc.date.accessioned2021-12-01T18:23:26Z
dc.date.available2021-12-01T18:23:26Z
dc.date.issued2020
dc.department[Belirlenecek]en_US
dc.description.abstractBackground/aim: This study is aimed to investigate the effects of vitamin D levels on sugammadex and neostigmine reversal times.Material and methods: Eighty patients between the ages of 18 and 65 years, with ASA I-III status who were undergoing surgery undergeneral anesthesia were included in the study. A double blind fashion was used to randomly divide all the patients into two groups. Atthe end of the operation, sugammadex 2 mg/kg was administered to one group (Group sugammadex) and atropine and neostigminewas administered to the other group (Group neostigmine) intravenously. In the data analysis stage, the group was divided into twosubgroups according to sugammadex and group neostigmine in itself, with vitamin D levels above and below 30 ng/mL. Statisticalanalysis was performed on these 4 groups (Group neostigmine and vitamin D < 30 ng/mL), (Group neostigmine and vitamin D ? 30ng/mL), ( Group sugammadex and vitamin D < 30 ng/mL), (Group sugammadex and vitamin D ? 30 ng/mL).When two responses to train of four (TOF) stimulation were taken, the following times were recorded until extubation phase. The timeuntil TOF value 50%, 70%, 90%, and extubation were recorded.Results: There were statistically significant differences between Group sugammadex and vitamin D < 30 ng/mL and Group sugammadexand vitamin D ? 30 ng/mL (P = 0.007) for extubation times and 50% TOF reach times (P = 0.015). However, there was no differenceobserved between Group neostigmine and vitamin D < 30 ng/mL and Group neostigmine and vitamin D ? 30 ng/mL (P = 0.999).Conclusion: Vitamin D deficiency is important for anesthesiologists in terms of muscle strength and extubation time. Vitamin Ddeficiency seems to affect sugammadex reverse times but seems not to affect neostigmine reverse times. This conclusion needs furtherstudies.en_US
dc.identifier.doi10.3906/sag-1901-115
dc.identifier.endpage755en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85087027093en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage749en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1901-115
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpVME5UZ3lNZz09
dc.identifier.urihttps://hdl.handle.net/20.500.12684/9705
dc.identifier.volume50en_US
dc.identifier.wosWOS:000613005100013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keywords]en_US
dc.titleThe effect of vitamin D status on different neuromuscular blocker agents reverse timeen_US
dc.typeArticleen_US

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