Keratoconus Could Be Associated With Psoriasis: Novel Findings From a Comparative Study

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dc.contributor.authorAkçam, Hanife Tuba
dc.contributor.authorKaragün, Ebru
dc.contributor.authorİritaş, İlter
dc.contributor.authorEyüp, Yavuz
dc.date.accessioned2020-04-30T23:18:48Z
dc.date.available2020-04-30T23:18:48Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionKaragun, Ebru/0000-0002-5032-7429en_US
dc.descriptionWOS: 000509673000013en_US
dc.descriptionPubMed: 31574049en_US
dc.description.abstractPurpose: To explore the relationship between keratoconus (KC) and psoriasis. Methods: One hundred ten eyes of 55 patients with psoriasis (study group, SG) and 110 eyes of age-sex-matched 55 healthy volunteers (control group, CG) were included in the study. All cases underwent a detailed dermatological and ophthalmological examination including corneal topography. Moreover, Psoriasis Area and Severity Index (PAST) scoring of the patients was carried out in the SG. A thorough comparison of pachymetric, aberrometric, and topometric values between the groups was performed, and the results were interpreted. A chi(2) test, Mann-Whitney U test, and Pearson correlation test were used for statistical assessment. Results: Although the average Kmax (44.6 in the SG; 44.5 in the CG; P = 0.613) and Belin/Ambrnsio enhanced ectasia total deviation value (1.34 in SG; 1.20 in CG; P = 0.880) were similar between the groups, the mean index of vertical asymmetry value in the SG (0.14 mm) was significantly higher than that in the CG (0.11 mm) (P = 0.041). Moreover, 28 eyes from 16 patients with psoriasis were found to be associated with KC because 26 of those 28 eyes were KC suspects and 2 of them were definite KC. A positive correlation was found among topometric parameters, especially between duration of the disease and PASI score. A negative correlation was discovered between topometric parameters and the early beginning of psoriasis. Conclusions: Serious changes in topography maps may occur in psoriatic patients. The changes were found to be more evident in the presence of a higher PAST score and the early beginning and longer duration of the disease. The results hinted a potential relationship between psoriasis and KC.en_US
dc.identifier.doi10.1097/ICO.0000000000002161en_US
dc.identifier.endpage1530en_US
dc.identifier.issn0277-3740
dc.identifier.issn1536-4798
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1524en_US
dc.identifier.urihttps://doi.org/10.1097/ICO.0000000000002161
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3534
dc.identifier.volume38en_US
dc.identifier.wosWOS:000509673000013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofCorneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcorneaen_US
dc.subjectinflammationen_US
dc.subjectkeratoconusen_US
dc.subjectpsoriasisen_US
dc.subjectskinen_US
dc.titleKeratoconus Could Be Associated With Psoriasis: Novel Findings From a Comparative Studyen_US
dc.typeArticleen_US

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