Incidental Papillary Thyroid Microcarcinoma in an Endemic Goiter Area

dc.contributor.authorGürleyik, Emin
dc.contributor.authorGürleyik, Günay
dc.contributor.authorKarapolat, Banu
dc.contributor.authorÖnsal, Ufuk
dc.date.accessioned2020-04-30T23:18:28Z
dc.date.available2020-04-30T23:18:28Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000370571200001en_US
dc.descriptionPubMed: 26949559en_US
dc.description.abstractClinical and pathological characteristics of incidental papillary thyroid microcancer cases, surgical, medical, and nuclear treatment methods, and patients' outcome were studied during follow-up period of 102 months. We studied 37 patients with incidental papillary thyroid microcancer (I-PTM). The surgical procedure was total thyroidectomy in 29 and hemithyroidectomy in 8 patients. Size, multifocality, and bilateralism of PTMfoci, thyroid capsule invasion, and presence of lymphovascular invasion were histopathological parameters. We analysed adjuvantmedical and nuclear treatment and patients' outcome during follow-up period of 102 (61-144) months. The prevalence rates of I-PTM were 9.4% in 395 thyroidectomy cases. Histopathological examination reported unifocal disease in 30 and multifocal disease in 7 (18%) patients. Multifocal disease was bilateral in 6 (20.1%) patients. The mean size of the PTMfoci was 4.88 mm. The rate of thyroid capsule invasion was 5.4%. All patients received a suppressive dose of LT4 to achieve a low serum TSH level. Adjuvant surgical and nuclear treatment was not performed in our cases. We did not find any negative changes in blood chemistry and ultrasound imaging, and any unfavourable events as locoregional and systemic recurrence. In conclusion, diagnosis of I-PTM is common that multifocality and bilateralism appear as pathologic features. The prognosis is excellent after surgical treatment and TSH suppression. Routine adjuvant nuclear treatment is unnecessary in majority of patients.en_US
dc.identifier.doi10.1155/2016/1784397en_US
dc.identifier.issn2090-8067
dc.identifier.issn2042-0072
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1155/2016/1784397
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3339
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofJournal Of Thyroid Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleIncidental Papillary Thyroid Microcarcinoma in an Endemic Goiter Areaen_US
dc.typeArticleen_US

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