Evaluation of outer hair cell function and medial olivocochlear efferent system in patients with type II diabetes mellitus

dc.contributor.authorKarabulut, Hayriye
dc.contributor.authorKarabulut, İsmail
dc.contributor.authorDağlı, Muharrem
dc.contributor.authorBayazıt, Yıldırım Ahmet
dc.contributor.authorBilen, Şule
dc.contributor.authorAydın, Yusuf
dc.contributor.authorBayramoğlu, İsmet
dc.date.accessioned2020-05-01T12:14:52Z
dc.date.available2020-05-01T12:14:52Z
dc.date.issued2014
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionKarabulut, Ismail/0000-0002-1339-5385en_US
dc.descriptionWOS: 000327592600026en_US
dc.descriptionPubMed: 25558576en_US
dc.description.abstractAim: This study was designed to investigate the function of outer hair cells and medial olivocochlear efferents in type II diabetes mellitus (DM). Materials and methods: There were 50 patients with type II DM and 51 age-and sex-matched healthy controls included in the study. Both groups were compared in terms of transient evoked otoacoustic emissions (TEOAEs), distortion product otoacoustic emissions (DPOAEs), and contralateral suppression of TEOAE. Results: Pure tone thresholds of the patients with type II DM were significantly higher than in the controls (P < 0.05). The TEOAE amplitudes at 1 kHz and at 1.5, 2, 3, 4, and 6 kHz signal-to-noise ratio amplitudes on DPOAE testing were significantly lower in the patients than controls (P < 0.05). There was no significant difference between the type II DM and control groups regarding contralateral suppression test results of TEOAEs. Conclusion: Type II DM seems to impact the auditory system at the cochlear level by affecting the functions of outer hair cells, and it results in elevation of the thresholds on audiometry and a decrease in the amplitudes of otoacoustic emissions.en_US
dc.identifier.doi10.3906/sag-1207-99en_US
dc.identifier.endpage156en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage150en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1207-99
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6372
dc.identifier.volume44en_US
dc.identifier.wosWOS:000327592600026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiabetes mellitusen_US
dc.subjectContralateral Suppressionen_US
dc.subjectMedial Olivocochlear Efferenten_US
dc.subjectTransient Evoked Otoacoustic Emissionsen_US
dc.subjectDistortion Product Ptoacoustic Emissionsen_US
dc.subjectHearingen_US
dc.titleEvaluation of outer hair cell function and medial olivocochlear efferent system in patients with type II diabetes mellitusen_US
dc.typeArticleen_US

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