Correlation between Vitamin D levels and thyroid autoantibodies in newly diagnosed hashimoto's thyroiditis patients

Basit Öğe Kaydı
dc.contributor.authorGenc, Ahmed Cihad
dc.contributor.authorTocoglu, Aysel
dc.contributor.authorAsan, Fatma Betul
dc.contributor.authorOnmez, Attila
dc.date.accessioned2025-10-11T20:47:38Z
dc.date.available2025-10-11T20:47:38Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground: Vitamin D plays a role in numerous metabolic functions. In this study we aimed to assess vitamin D levels in Hashimoto's Thyroditis (HT) patients, and demonstrate the relationship between these levels and thyroid function tests or thyroid autoantibodies. Methods: A retrospective analysis of 112 newly diagnosed euthyroid HT (EHT) patients and 178 healthy controls was carried out. 25-OH D level was classified as vitamin D deficiency, vitamin D insufficiency, and vitamin D sufficient. Results: Mean age was 35.33 +/- 11.54 years in the patient group, and 35.84 +/- 10.9 in the control group (p=0.777). Compared with the healthy controls, patients in the EHT group had significantly lower vitamin D levels (p=0.007), and a significantly higher prevalence of vitamin D deficiency (p=0.001). While there was a negative correlation between vitamin D levels and anti-TPO values (r=-0.133, p=0.023), there was no significant relationship between vitamin D and TSH, fT4, fT3, and anti-TG values (p>0.05). Conclus & imath;ons: This study showed that EHT patients had lower vitamin D levels compared to healthy controls, and there was a significant negative correlation between vitamin D levels and anti-TPO levels. Based on our study, patients diagnosed with HT should undergo vitamin D screening, and replacement if necessary.en_US
dc.identifier.doi10.4314/ahs.v25i2.22
dc.identifier.endpage175en_US
dc.identifier.issn1680-6905
dc.identifier.issn1729-0503
dc.identifier.issue2en_US
dc.identifier.pmid40837651en_US
dc.identifier.scopus2-s2.0-105012114141en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage168en_US
dc.identifier.urihttps://doi.org/10.4314/ahs.v25i2.22
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21496
dc.identifier.volume25en_US
dc.identifier.wosWOS:001533134400022en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMakerere Univ, Coll Health Sciences,Sch Meden_US
dc.relation.ispartofAfrican Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectHashimoto's Thyroiditisen_US
dc.subjectThyroglobulin Antibodyen_US
dc.subjectThyroid Peroxidase Antibodyen_US
dc.subjectVitamin Den_US
dc.titleCorrelation between Vitamin D levels and thyroid autoantibodies in newly diagnosed hashimoto's thyroiditis patientsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu