Correlation between Vitamin D levels and thyroid autoantibodies in newly diagnosed hashimoto's thyroiditis patients
Küçük Resim Yok
Tarih
2025
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Makerere Univ, Coll Health Sciences,Sch Med
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Vitamin D plays a role in numerous metabolic functions. In this study we aimed to assess vitamin D levels in Hashimoto's Thyroditis (HT) patients, and demonstrate the relationship between these levels and thyroid function tests or thyroid autoantibodies. Methods: A retrospective analysis of 112 newly diagnosed euthyroid HT (EHT) patients and 178 healthy controls was carried out. 25-OH D level was classified as vitamin D deficiency, vitamin D insufficiency, and vitamin D sufficient. Results: Mean age was 35.33 +/- 11.54 years in the patient group, and 35.84 +/- 10.9 in the control group (p=0.777). Compared with the healthy controls, patients in the EHT group had significantly lower vitamin D levels (p=0.007), and a significantly higher prevalence of vitamin D deficiency (p=0.001). While there was a negative correlation between vitamin D levels and anti-TPO values (r=-0.133, p=0.023), there was no significant relationship between vitamin D and TSH, fT4, fT3, and anti-TG values (p>0.05). Conclus & imath;ons: This study showed that EHT patients had lower vitamin D levels compared to healthy controls, and there was a significant negative correlation between vitamin D levels and anti-TPO levels. Based on our study, patients diagnosed with HT should undergo vitamin D screening, and replacement if necessary.
Açıklama
Anahtar Kelimeler
Hashimoto's Thyroiditis, Thyroglobulin Antibody, Thyroid Peroxidase Antibody, Vitamin D
Kaynak
African Health Sciences
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
25
Sayı
2
