Does Suture Material Affect Uterine Scar Healing After Cesarean Section? Results from a Randomized Controlled Trial

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dc.contributor.authorBaşbuğ, Alper
dc.contributor.authorDoğan, Ozan
dc.contributor.authorKaya, Aşkı Ellibeş
dc.contributor.authorPulatoğlu, Çiğdem
dc.contributor.authorÇağlar, Mete
dc.date.accessioned2020-05-01T09:11:29Z
dc.date.available2020-05-01T09:11:29Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptiondogan, ozan/0000-0002-0016-8749; ELLIBES KAYA, ASKI/0000-0002-1323-7416en_US
dc.descriptionWOS: 000498685000012en_US
dc.descriptionPubMed: 29667541en_US
dc.description.abstractBackground: Impaired healing of the uterine scar after cesarean has been associated with adverse gynecological and obstetric outcomes. Although a large number of studies have been conducted on the events leading to this, information obtained from prospective randomized studies examining the role of suture material in the formation of cesarean scar defect (CSD) is lacking. Objective: To evaluate the effects of synthetic suture materials on CSD formation. Study design: We performed a two-arm 1:1 randomized study in women with singleton pregnancies undergoing elective primary cesarean delivery after the 38th week of gestation. Uterine scar closure was performed using synthetic absorbable monofilament and multifilament sutures. The primary outcome was residual myometrial thickness (RMT) in the area of the scar, measured by transvaginal ultrasound 6-9 months after birth. Secondary outcomes included differences in mean operative time, mean estimated blood loss at the time of surgery, and the rates of postoperative gynecological sequelae. Results: Complete follow-up was obtained from 94 (88%) of 107 participants. RMT was thicker in the monofilament compared to the multifilament suture group (5.5 +/- 2.24 vs. 4.18 +/- 1.76, p = 0.01). Hemoglobin delta was higher in the monofilament suture group (1.59 +/- 0.96 vs. 1.25 +/- 0.60, p = 0.04). There was no statistically significant difference between the monofilament suture and multifilament suture groups in terms of gynecological sequelae. Conclusion: Closure of the uterine scar with monofilament suture has a positive effect on scar healing and increases RMT thickness.en_US
dc.identifier.doi10.1080/08941939.2018.1458926en_US
dc.identifier.endpage769en_US
dc.identifier.issn0894-1939
dc.identifier.issn1521-0553
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage763en_US
dc.identifier.urihttps://doi.org/10.1080/08941939.2018.1458926
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5623
dc.identifier.volume32en_US
dc.identifier.wosWOS:000498685000012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofJournal Of Investigative Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcesareanen_US
dc.subjectisthmoceleen_US
dc.subjectscar defecten_US
dc.subjectsuture materialen_US
dc.titleDoes Suture Material Affect Uterine Scar Healing After Cesarean Section? Results from a Randomized Controlled Trialen_US
dc.typeArticleen_US

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