Does cigarette smoking really have detrimental effects on outcomes of IVF?

Basit Öğe Kaydı
dc.contributor.authorÇınar, Özgür
dc.contributor.authorDilbaz, Serdar
dc.contributor.authorTerzioğlu, Füsun
dc.contributor.authorKarahalil, Bensu
dc.contributor.authorYücel, Çiğdem
dc.contributor.authorTürk, Rukiye
dc.contributor.authorKöse, S. Kenan
dc.date.accessioned2020-05-01T09:11:28Z
dc.date.available2020-05-01T09:11:28Z
dc.date.issued2014
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000333505500019en_US
dc.descriptionPubMed: 24424210en_US
dc.description.abstractObjective: Cigarette smoke contains many toxic chemicals associated with poor reproductive outcome and reduced fertility. It also has a negative effect on sperm motility and morphology. The aim of this study was to analyze the effects of male and female cigarette smoking on the outcomes of in vitro fertilization (IVF). Study design: In this comparative prospective analysis, the effects of smoking on outcomes of IVF including semen parameters, oocyte quality, fertilization rate, transfer day embryo scores and pregnancy rates were analyzed. For this purpose, patients were grouped based on their follicular or seminal fluid cotinine (a nicotine metabolite) levels as smokers and non-smokers (non-smokers: female (n = 171), male (n = 118), smokers: female (n = 43), male (n = 96)). Results: The mean age and baseline hormonal levels of all groups were found to be comparable. While the numbers of total and mature oocytes collected were higher in the smoker group (p = 0.005 and p = 0.006, respectively), oocyte quality index, fertilization rate, embryo development rate and pregnancy rate were not significantly different between the groups (p > 0.05). Analysis based on the type of ovarian hyperstimulation protocol (GnRH agonist, antagonist and others) showed that within the antagonist group the mean age of smokers was significantly lower and the total number of collected oocytes was significantly higher compared with non-smokers. Cigarette smoking among men did not have a significant negative effect on outcomes of IVF whether their partners were smokers or nonsmokers. Regression analysis did not give any significant difference when male and/or female smoking status was analyzed for fertilization rates, transferred embryo qualities and clinical pregnancy rates. Conclusion: Cigarette smoking does not have detrimental effects on outcomes of IVF. (C) 2014 Elsevier Ireland Ltd. All rights reserved.en_US
dc.description.sponsorshipScientific Research Section of Hacettepe UniversityHacettepe Universityen_US
dc.description.sponsorshipA part of this study was supported by Scientific Research Section of Hacettepe University.en_US
dc.identifier.doi10.1016/j.ejogrb.2013.12.026en_US
dc.identifier.endpage110en_US
dc.identifier.issn0301-2115
dc.identifier.issn1872-7654
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage106en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2013.12.026
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5610
dc.identifier.volume174en_US
dc.identifier.wosWOS:000333505500019en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofEuropean Journal Of Obstetrics & Gynecology And Reproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCigarette smokingen_US
dc.subjectCotinineen_US
dc.subjectOutcomes of IVFen_US
dc.subjectHyperstimulation protocolen_US
dc.titleDoes cigarette smoking really have detrimental effects on outcomes of IVF?en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
5610.pdf
Boyut:
300.65 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu