Synthesis and Characterization of Copper-Nanoflowers with the Utilization of Medicinal Plant Extracts for Enhanced Various Enzyme Inhibitory Activities
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Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, organic-inorganic hybrid nanoflowers were synthesized using methanolic extracts of the medicinal plants Ajuga chamaepitys subsp. chia var. chia, Achillea wilhelmsii, Bongardia chrysogonum, Malva sylvestris, Phlomis grandiflora var. grandiflora, Verbascum sp. together with copper ions (Cu2+). The synthesized plant extract based-inorganic hybrid nanoflowers (PE-ihNFs) of A. chamaepitys subsp. chia var. chia (Ac-ihNFs), A. wilhelmsii (Aw-ihNfs), B. chrysogonum (Bc-ihNFs), M. sylvestris (Ms-ihNFs) P. grandiflora var. grandiflora (Pg-ihNFs), and Verbascum sp. (Vs-ihNFs) were characterized by Scanning Electron Microscopy (SEM), Energy-Dispersive X-ray (EDX), Fourier transform infrared spectrometry (FTIR), and X-Ray Diffraction (XRD). Also, several enzymes were selected to evaluate the enzyme inhibition activities of the synthesized PE-ihNFs. For the first-time, enzymes, tyrosinase, alpha-amylase and alpha-glucosidase, acetyl and butyryl cholinesterase inhibition activities of the PE-ihNFs with comparison to their plain plant extracts were evaluated in vitro. Results show that the among all the analyzed PE-ihNFs, demonstrated better alpha-glucosidase & alpha-amylase enzyme inhibition activity compared to the plain extracts. These initial studies are promising for the synthesis of these hybrid nanoflowers containing medicinal plant extracts, which might have commercial applications in the pharmaceutical and dermo-cosmetics industries.
Açıklama
Anahtar Kelimeler
Enzyme Inhibitions; Hybrid Nanoflowers; Medicinal Plants; Plants Extract, Inorganic Hybrid Nanoflowers; Bioassay-Guided Isolation; Antimicrobial Activity; Traditional Medicine; Chemical-Composition; Iridoid Glycosides; Alpha-Glucosidase; Essential Oil; Tyrosinase; L.
Kaynak
Chemistry & Biodiversity
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
19
Sayı
11
