Effects of 900-MHz electromagnetic fields exposure throughout middle/late adolescence on the kidney morphology and biochemistry of the female rat

dc.contributor.authorOkatan, Derya Öztürk
dc.contributor.authorOkatan, Ali Ertan
dc.contributor.authorHancı, Hatice
dc.contributor.authorDemir, Selim
dc.contributor.authorYaman, Serap Özer
dc.contributor.authorÇolakoğlu, Serdar
dc.contributor.authorOdacı, Ersan
dc.date.accessioned2020-05-01T09:11:51Z
dc.date.available2020-05-01T09:11:51Z
dc.date.issued2018
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionDemir, Selim/0000-0002-1863-6280en_US
dc.descriptionWOS: 000446534300004en_US
dc.descriptionPubMed: 30009691en_US
dc.description.abstractThe effect of the electromagnetic field (EMF) established when cell phones are in use on human health, and particularly the head, has been the subject of major scientific research. Phones are usually carried near the lumbar region when not in use, and the kidneys will also inevitably be affected by such fields. We investigated the effects on the kidneys of female rats exposed to a continuous 900-megahertz (MHz) EMF for 1 h daily in mid-late adolescence. Control, sham, and EMF groups were established. The EMF was applied to the application group rats daily on postnatal days 35-59. A pseudo-megahertz effect was applied to sham group rats. All animals were euthanized on postnatal day 60. Right kidney tissues were subjected to routine procedures. Malondialdehyde, total antioxidant status, and total oxidant status (TOS) were investigated in left kidneys, and the oxidative stress index (OSI) was also calculated from these. Histopathological analysis revealed no pathology in either the control or sham groups. However, findings including hemorrhage in glomerulus, vacuolization and irregularity in the proximal and distal tubular epithelium, diffuse glomerular degeneration and edema, occasional degeneration in Bowman capsules, hemorrhage in the medullary region, disturbed nucleus location and morphology, and tubular edema in the cortex were observed in the EMF groups. TOS and OSI values were lower in the EMF group (9.4316 +/- 1.0211 and 0.8461 +/- 0.0826, respectively) and the sham group (8.2171 +/- 0.6437 and 0.7358 +/- 0.0545, respectively) than in the control group (11.1522 +/- 1.3389 and 1.0085 +/- 0.1174, respectively) (p < 0.05). In conclusion, exposure to a continuous 900-MHz EMF for 1 h daily during middle and late adolescence may cause various changes in the female rat kidney at postnatal day 60.en_US
dc.identifier.doi10.1177/0748233718781292en_US
dc.identifier.endpage702en_US
dc.identifier.issn0748-2337
dc.identifier.issn1477-0393
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage693en_US
dc.identifier.urihttps://doi.org/10.1177/0748233718781292
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5792
dc.identifier.volume34en_US
dc.identifier.wosWOS:000446534300004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofToxicology And Industrial Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectromagnetic fielden_US
dc.subjectkidneyen_US
dc.subjectcell phoneen_US
dc.subjectoxidative stressen_US
dc.subjectfemale raten_US
dc.subjectadolescenceen_US
dc.titleEffects of 900-MHz electromagnetic fields exposure throughout middle/late adolescence on the kidney morphology and biochemistry of the female raten_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
5792.pdf
Boyut:
1.02 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text