Synthesis, Antibacterial, Antiurease, and Antioxidant Activities of Some New 1,2,4-Triazole Schiff Base and Amine Derivatives

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dc.contributor.authorSökmen, Bahar Bilgin
dc.contributor.authorGümrükçüoğlu, Nurhan
dc.contributor.authorUğraş, Serpil
dc.contributor.authorŞahin, Hüseyin
dc.contributor.authorSağkal, Yasemin
dc.contributor.authorUğraş, Halil İbrahim
dc.date.accessioned2020-04-30T23:32:28Z
dc.date.available2020-04-30T23:32:28Z
dc.date.issued2015
dc.departmentDÜ, Ziraat Fakültesi, Tarla Bitkileri Bölümüen_US
dc.descriptionSahin, Huseyin/0000-0002-6018-1494en_US
dc.descriptionWOS: 000348103100007en_US
dc.descriptionPubMed: 25342259en_US
dc.description.abstractThe acylhydrazone compound named ethyl N'-furan-2-carbonylbenzohydrazonate was synthesized by the condensation of ethyl benzimidate hydrochloride with furan-2-carbohydrazide. The treatment of the acylhydrazone with hydrazine hydrate afforded 4-amino-3-furan-2-yl-5-phenyl-1,2,4-triazole. The usage of this compound with various aromatic aldehydes resulted in the formation of 4-arylidenamino-3-furan-2-yl-5-phenyl-1,2,4-triazoles. Sodium borohydride reduction of 4-arylidenamino derivatives afforded 4-alkylamino-3-furan-2-yl-5-phenyl-1,2,4-triazoles. The obtained products were identified by FT-IR, H-1-NMR, C-13-NMR. A series of compounds were evaluated for their antibacterial, antiurease, and antioxidant activities. The results showed that the synthesized new compounds had effective antiurease and antioxidant activities.en_US
dc.identifier.doi10.1007/s12010-014-1307-2en_US
dc.identifier.endpage714en_US
dc.identifier.issn0273-2289
dc.identifier.issn1559-0291
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage705en_US
dc.identifier.urihttps://doi.org/10.1007/s12010-014-1307-2
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4727
dc.identifier.volume175en_US
dc.identifier.wosWOS:000348103100007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofApplied Biochemistry And Biotechnologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcyl hydrazoneen_US
dc.subject1,2,4-triazoleen_US
dc.subjectSchiff baseen_US
dc.subjectReductionen_US
dc.subjectUrease inhibition activityen_US
dc.subjectAntioxidant activityen_US
dc.titleSynthesis, Antibacterial, Antiurease, and Antioxidant Activities of Some New 1,2,4-Triazole Schiff Base and Amine Derivativesen_US
dc.typeArticleen_US

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