Evaluation of cardiovascular risk in children with solitary functioning kidney

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dc.authoridSav, Nadide Melike/0000-0003-1520-6426
dc.authoridCan, Betül/0000-0001-8430-5298
dc.authoridUçar, Birsen/0000-0002-7746-6058
dc.authoridAlatas, I. Ozkan/0000-0002-1753-8873
dc.authorwosidCan, Betül/GQQ-2942-2022
dc.authorwosidSav, Nadide Melike/GWV-4236-2022
dc.contributor.authorSav, Nadide Melike
dc.contributor.authorKosger, Pelin
dc.contributor.authorCan, Betül
dc.contributor.authorÇetin, Nuran
dc.contributor.authorUçar, Birsen
dc.contributor.authorAlataş, Özkan
dc.contributor.authorAkyüz, Fahrettin
dc.date.accessioned2023-07-26T11:50:27Z
dc.date.available2023-07-26T11:50:27Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractBackground The present study investigates cardiovascular risk and kidney damage in patients with solitary kidneys. Methods Included in the study were 40 children with a unilateral functioning kidney and 60 healthy controls, all of whom were evaluated for carotid intima-media thickness, ischemia-modified albumin and oxidative stress parameters, and 24-h ambulatory blood pressure monitoring. Results Serum creatinine and urine microalbumin levels were higher and creatinine clearance was lower in the patient group than in the control group, and serum ischemia-modified albumin, carotid intima-media thickness, aldosterone, plasma renin activity and blood pressure were all higher in the patient group than in the control group. In addition, the patient group was showed a non-dipper pattern. Conclusion Children with a normal functioning solitary kidney are likely at higher risk of developing cardiovascular disease and such patients should be followed closely before marked kidney impairment occurs.en_US
dc.identifier.doi10.1007/s10157-021-02169-7
dc.identifier.endpage423en_US
dc.identifier.issn1342-1751
dc.identifier.issn1437-7799
dc.identifier.issue5en_US
dc.identifier.pmid35037126en_US
dc.identifier.scopus2-s2.0-85123067673en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage415en_US
dc.identifier.urihttps://doi.org/10.1007/s10157-021-02169-7
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12350
dc.identifier.volume26en_US
dc.identifier.wosWOS:000743002500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSav, Nadide Melike
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofClinical and Experimental Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectSolitary Kidney; Cardiovascular Risk; Children; Carotid Intima-Media Thickness; Ischemia-Modified Albumin; 24-H Ambulatory Blood Pressure Monitoringen_US
dc.subjectIschemia-Modified Albumin; Blood-Pressure; Myocardial-Ischemia; Oxidative Stress; Heart-Failure; Disease; Binding; Marker; Assay; Proteinuriaen_US
dc.titleEvaluation of cardiovascular risk in children with solitary functioning kidneyen_US
dc.typeArticleen_US

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