Evaluation of cardiovascular risk in children with solitary functioning kidney
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Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background The present study investigates cardiovascular risk and kidney damage in patients with solitary kidneys. Methods Included in the study were 40 children with a unilateral functioning kidney and 60 healthy controls, all of whom were evaluated for carotid intima-media thickness, ischemia-modified albumin and oxidative stress parameters, and 24-h ambulatory blood pressure monitoring. Results Serum creatinine and urine microalbumin levels were higher and creatinine clearance was lower in the patient group than in the control group, and serum ischemia-modified albumin, carotid intima-media thickness, aldosterone, plasma renin activity and blood pressure were all higher in the patient group than in the control group. In addition, the patient group was showed a non-dipper pattern. Conclusion Children with a normal functioning solitary kidney are likely at higher risk of developing cardiovascular disease and such patients should be followed closely before marked kidney impairment occurs.
Açıklama
Anahtar Kelimeler
Solitary Kidney; Cardiovascular Risk; Children; Carotid Intima-Media Thickness; Ischemia-Modified Albumin; 24-H Ambulatory Blood Pressure Monitoring, Ischemia-Modified Albumin; Blood-Pressure; Myocardial-Ischemia; Oxidative Stress; Heart-Failure; Disease; Binding; Marker; Assay; Proteinuria
Kaynak
Clinical and Experimental Nephrology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
26
Sayı
5
