The impact of metabolic syndrome on carotid intima media thickness

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dc.contributor.authorAydın, Mesut
dc.contributor.authorBulur, Serkan
dc.contributor.authorAlemdar, Recai
dc.contributor.authorYalçın, Sübhan
dc.contributor.authorTürker, Yasemin
dc.contributor.authorBaşar, Cengiz
dc.contributor.authorÖzhan, Hakan
dc.date.accessioned2020-04-30T23:33:46Z
dc.date.available2020-04-30T23:33:46Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000325204600005en_US
dc.descriptionPubMed: 24065221en_US
dc.description.abstractOBJECTIVES: Metabolic syndrome (MetS) is a cluster of metabolic abnormalities involving several cardiovascular risk factors. Carotid intima media thickness (CIMT) is an important early screening tool to assess subclinical manifestation of cardiovascular and metabolic diseases. We aimed to investigate the impact of MetS on CIMT in a large scaled community based study. METHODS: The study was conducted on 2102 participants. Carotid intima media thickness was measured in all of the participants. The study sample was divided into 4 groups; Group 1 subjects with a body mass index (BMI) < 25.0 kg/m(2) [n = 499 (MetS- = 488, MetS+ = 11)], Group 2 BMI between 25.0 and 29.9 kg/m(2) [n = 693 (MetS-= 559, MetS+ = 134)], Group 3 BMI between >= 30 kg/m(2) and 39.9 kg/m(2) [n = 822 (MetS-= 375, MetS+ = 477)], and Group 4 BMI >= 40 kg/m(2) [n = 88 (MetS-= 27, MetS+ = 61)]. RESULTS: Carotid intima media thickness was higher in the individuals with MetS compared to their normal counterparts. Furthermore, the sub-group analysis showed that CIMT values in Group 1 (0.55 +/- 0.18 vs 0.82 +/- 0.70; p < 0.001), Group 2 (0.59 +/- 0.20 vs 0.68 +/- 0.18; p < 0.001) and Group 3 (0.61 +/- 0.15 vs 0.65 +/- 0.18; p < 0.001) were significantly higher in subjects with MetS compared to their normal counterparts, whereas the values were similar in Group 4 (0.62 +/- 0.13 vs 0.65 +/- 0.17; p = 0.363). CONCLUSIONS: Carotid intima media thickness of overweight, obese and normal weight individuals without MetS were lower than their counterparts with MetS. MetS had no impact on CIMT in morbid obese individuals possibly due to established insulin resistance earlier than MetS.en_US
dc.identifier.endpage2301en_US
dc.identifier.issn1128-3602
dc.identifier.issue17en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2295en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5041
dc.identifier.volume17en_US
dc.identifier.wosWOS:000325204600005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectCarotid intima media thicknessen_US
dc.titleThe impact of metabolic syndrome on carotid intima media thicknessen_US
dc.typeArticleen_US

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