Tramadol and levobupivacaine wound infiltration at Cesarean delivery for postoperative analgesia

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dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorAlbayrak, Mustafa
dc.contributor.authorYorulmaz, İlknur Suidiye
dc.contributor.authorÖzdemir, İsmail
dc.date.accessioned2020-04-30T23:34:58Z
dc.date.available2020-04-30T23:34:58Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionYorulmaz, Ilknur Suidiye/0000-0002-1441-6360en_US
dc.descriptionWOS: 000317366400003en_US
dc.descriptionPubMed: 23135774en_US
dc.description.abstractThe aim of the present study was to investigate whether levobupivacaine and tramadol wound infiltration decreases postoperative pain following Cesarean section and reduces the need for analgesics in the immediate post-delivery period. Ninety patients (aged 18-40 years) scheduled for elective Cesarean section under general anesthesia were randomly allocated to one of the three groups: the placebo group (group P) received 20 mL local wound infiltration with 0.9 % saline solution; the levobupivacaine group (group L) received 20 mL local wound infiltration with levobupivacaine 0.25 %; and the tramadol group (group T) received 20 mL local wound infiltration with 1.5 mg/kg tramadol within 0.9 % saline solution. Following the closure of the uterine incision and the rectus fascia, 20 mL solution was infiltrated subcutaneously along the skin wound edges. The primary outcome was 24-h tramadol consumption. Secondary outcomes were recorded VAS scores, diclofenac requirement, fever, vomiting, and wound infection. At 15 min postoperatively, VAS values were lower in groups T and L than group P (P = 0.0001). The mean 24-h tramadol consumption was lowest in group T (P = 0.0001) and it was lower in the group L compared to group P (P = 0.007) (401.6, 483.3, and 557.5 mg for T, L, and P groups, respectively). There was no difference among groups regarding the need for supplemental analgesia (rescue diclofenac doses) (P > 0.05). We conclude that wound infiltration with tramadol and levobupivacaine in patients having Cesarean section under general anesthesia may be a good choice for postoperative analgesia.en_US
dc.identifier.doi10.1007/s00540-012-1510-7en_US
dc.identifier.endpage179en_US
dc.identifier.issn0913-8668
dc.identifier.issn1438-8359
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage175en_US
dc.identifier.urihttps://doi.org/10.1007/s00540-012-1510-7
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5253
dc.identifier.volume27en_US
dc.identifier.wosWOS:000317366400003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Japan Kken_US
dc.relation.ispartofJournal Of Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLevobupivacaineen_US
dc.subjectTramadolen_US
dc.subjectPostoperative analgesiaen_US
dc.subjectInfiltrationen_US
dc.titleTramadol and levobupivacaine wound infiltration at Cesarean delivery for postoperative analgesiaen_US
dc.typeArticleen_US

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