Pathological effects of prenatal exposure to a 900 MHz electromagnetic field on the 21-day-old male rat kidney

dc.contributor.authorOdacı, Ersan
dc.contributor.authorÜnal, Deniz
dc.contributor.authorMercantepe, Tolga
dc.contributor.authorTopal, Z.
dc.contributor.authorHancı, Hatice
dc.contributor.authorTüredi, Sibel
dc.contributor.authorÇolakoğlu, Serdar
dc.date.accessioned2020-04-30T23:20:36Z
dc.date.available2020-04-30T23:20:36Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionMercantepe, Tolga/0000-0002-8506-1755; Erol, Huseyin/0000-0002-9121-536X; Erol, Huseyin Serkan/0000-0002-9121-536Xen_US
dc.descriptionWOS: 000352109500002en_US
dc.descriptionPubMed: 25158858en_US
dc.description.abstractWe investigated the effects on kidney tissue of 900 megahertz (MHz) EMF applied during the prenatal period. Pregnant rats were exposed to 900 MHz EMF, 1 h/day, on days 13-21 of pregnancy; no procedure was performed on control group pregnant rats or on mothers or newborns after birth. On postnatal day 21, kidney tissues of male rat pups from both groups were examined by light and electron microscopy. Malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glutathione levels also were investigated. Light microscopy revealed some degenerative changes in the tubule epithelium, small cystic formations in the primitive tubules and large cysts in the cortico-medullary or medullary regions in the experimental group. Electron microscopy revealed a loss of peritubular capillaries and atypical parietal layer epithelial cells in the experimental group. Biochemical analysis showed significantly increased MDA levels in the experimental group and decreased SOD and CAT levels. EMF applied during the prenatal period can caused pathological changes in kidney tissue in 21-day-old male rats owing to oxidative stress and decreased antioxidant enzyme levels.en_US
dc.identifier.doi10.3109/10520295.2014.947322en_US
dc.identifier.endpage101en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage93en_US
dc.identifier.urihttps://doi.org/10.3109/10520295.2014.947322
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4040
dc.identifier.volume90en_US
dc.identifier.wosWOS:000352109500002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnic & Histochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantioxidant enzymesen_US
dc.subjectcell phoneen_US
dc.subjectelectromagnetic fielden_US
dc.subjectkidneyen_US
dc.subjectmale raten_US
dc.titlePathological effects of prenatal exposure to a 900 MHz electromagnetic field on the 21-day-old male rat kidneyen_US
dc.typeArticleen_US

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