Hoarseness and laryngopharyngeal reflux: a cause and effect relationship or coincidence?

dc.contributor.authorÖztürk, Özcan
dc.contributor.authorÖz, Ferhan
dc.contributor.authorKarakullukçu, Barış
dc.contributor.authorOğhan, Fatih
dc.contributor.authorGüçlü, Ender
dc.contributor.authorAda, Mehmet
dc.date.accessioned2020-05-01T12:10:27Z
dc.date.available2020-05-01T12:10:27Z
dc.date.issued2006
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000240396200010en_US
dc.descriptionPubMed: 16816932en_US
dc.description.abstractThe role of laryngopharyngeal reflux (LPR) on hoarseness is widely assumed and accepted. Few articles present objective information on the subject. One of the main problems in establishing a relationship is our lack of knowledge of what is normal. We compared patients with chronic hoarseness and healthy controls to establish three goals: (1) to demonstrate the presence of additional symptoms and signs of LPR in patients with hoarseness; (2) to find the prevalence of LPR by utilizing 24 h double-probe in patients with hoarseness and compare it with that of the control group; (3) to contribute data to establish prevalence of LPR in healthy population. Forty-three patients with hoarseness and 20 healthy volunteers were enrolled in the study. All the patients in the study group had hoarseness of more than 3 months duration. The subjects recieved videolaryngoscopic evaluation and 24 h double-probe pH monitoring, and the results were compared. In the study group, 27 patients (62.8%) out of 43 had LPR episodes, compared to 6 (30%) of 20 healthy volunteers. Mean number of LPR episodes recorded by the pharyngeal probe was 7.0 [standard deviation (SD): 8.8] in 24 h, and this was significantly higher than that of the healthy controls [0.9/24 h (SD: 1.9)] (P = 0.003). Mean number of LPR episodes of the study group in upright position was 5.8 (SD: 7,0) and in supine position was 1.2 (SD: 3.3). These numbers were also significantly higher from the controls (P = 0.005 and P = 0.014 respectively). The results of this study show that: (1) most common additional symptoms were heartburn and chronic throat clearing and most common finding is pachydermia; (2) LPR incidence in patients with chronic hoarseness is significantly higher than the LPR incidence in healthy controls; (3) LPR is present in healthy people. However, the severity of LPR seems to be the causative factor rather than its presence.en_US
dc.identifier.doi10.1007/s00405-006-0097-8en_US
dc.identifier.endpage939en_US
dc.identifier.issn0937-4477
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage935en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-006-0097-8
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6201
dc.identifier.volume263en_US
dc.identifier.wosWOS:000240396200010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives Of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthoarsenessen_US
dc.subjectlarynghopharyngeal refluxen_US
dc.subjectpH monitoringen_US
dc.subjectpharyngeal probeen_US
dc.titleHoarseness and laryngopharyngeal reflux: a cause and effect relationship or coincidence?en_US
dc.typeArticleen_US

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