Reporting the clinical spectrum of children with IgAV in a retrospective 24-year cohort: Influences of age and sex on clinical presentation

Basit Öğe Kaydı
dc.authoridYıldırım, Sema/0000-0001-7311-519Xen_US
dc.authorscopusid56779628500en_US
dc.authorscopusid14518977800en_US
dc.authorwosidYıldırım, Sema/GQA-9215-2022en_US
dc.contributor.authorYıldırım, Sema
dc.contributor.authorErguven, Muferet
dc.date.accessioned2024-08-23T16:03:23Z
dc.date.available2024-08-23T16:03:23Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground/aim: Immunoglobulin A vasculitis (IgAV) is one of the most common types of vasculitis in children. The aims of this study were to investigate the clinical characteristics of the disease, and the effects of age and sex on the clinical course in children with IgAV. Materials and methods: This was a retrospective study including pediatric patients diagnosed with IgAV who attended follow-ups at the pediatric rheumatology department of a tertiary healthcare institution between January 1997 and December 2020. The patients were grouped and compared according to sex and age at diagnosis (<7 years vs. >= 7 years). Results: The study included 709 children with IgAV, 392 (55.3%) of whom were male. The mean age at diagnosis was 7.9 +/- 3.2 years. The most common disease onset season was autumn (31.2%). Upper respiratory infections (27.8%) were the most common predisposing factors. Gastrointestinal system (GIS), joint, and renal involvement were observed in 52.8%, 47.5%, and 17.5% of patients, respectively. Renal involvement, GIS involvement, and disease relapse were significantly more common among those diagnosed after 7 years of age compared to those diagnosed before the age of 7 (p < 0.001, p = 0.033, and p < 0.001, respectively). Scrotal involvement and subcutaneous edema were more common among those diagnosed at younger than 7 years compared to those aged >= 7 years at diagnosis (p < 0.001 and p = 0.016, respectively). GIS involvement was more frequently seen in males compared to females (p = 0.046). Conclusion: It was demonstrated that being >= 7 years of age at diagnosis or being a male were associated with higher likelihood of renal and GIS involvement in children with IgAV.en_US
dc.identifier.doi10.55730/1300-0144.5700
dc.identifier.endpage1347en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5en_US
dc.identifier.pmid38813037en_US
dc.identifier.scopus2-s2.0-85175582007en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1339en_US
dc.identifier.trdizinid1209081en_US
dc.identifier.urihttps://doi.org/10.55730/1300-0144.5700
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1209081
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13716
dc.identifier.volume53en_US
dc.identifier.wosWOS:001108669900009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAgeen_US
dc.subjectchildrenen_US
dc.subjectclinical manifestationsen_US
dc.subjectIgA vasculitisen_US
dc.subjectsexen_US
dc.subjectHenoch-Schonlein Purpuraen_US
dc.subjectRisk-Factorsen_US
dc.subjectNephritisen_US
dc.subjectChildhooden_US
dc.subjectClassificationen_US
dc.subjectManagementen_US
dc.subjectDiagnosisen_US
dc.subjectFeaturesen_US
dc.subjectSpainen_US
dc.titleReporting the clinical spectrum of children with IgAV in a retrospective 24-year cohort: Influences of age and sex on clinical presentationen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
13716.pdf
Boyut:
123.2 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu