Ghrelins, obestatin, nesfatin-1 and leptin levels in pregnant women with and without hyperemesis gravidarum

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dc.contributor.authorGüngör, Sami
dc.contributor.authorGürateş, Bilgin
dc.contributor.authorAydın, Süleyman
dc.contributor.authorŞahin, İbrahim
dc.contributor.authorKavak, Salih Burçin
dc.contributor.authorKumru, Selahattin
dc.contributor.authorÖzdemir, Nazan
dc.date.accessioned2020-05-01T12:10:15Z
dc.date.available2020-05-01T12:10:15Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionCatak, Zekiye/0000-0003-1973-3645; KUMRU, Selahattin/0000-0001-6615-7666; CITIL, Cihan/0000-0002-3006-4035en_US
dc.descriptionWOS: 000319549100025en_US
dc.descriptionPubMed: 23380589en_US
dc.description.abstractObjectives: The goal of this study was to compare levels of acyl and des-acyl ghrelin, obestatin, nesfatin-1 and leptin in healthy gravidas to hyperemesis gravidarum (HG) patients. Design and methods: Twenty pregnant women with HG and twenty healthy pregnant women all of similar ages, BMI and all at similar pregnancy development comprised the study cohort. Fasting serum samples were obtained and measured for acyl and des-acyl ghrelin, leptin, obestatin and nesfatin-1. Results: Nesfatin-1 concentrations in the HG group were higher compared to the control group whereas; leptin concentrations during pregnancy were lower in the HG group as compared to the control group. The two groups did not differ with regard to acyl and des-acyl ghrelin and obestatin. Conclusion: This pilot study suggests a possible role of leptin and nesfatin-1, which might be involved in the pathology of the disease. (C) 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.en_US
dc.description.sponsorshipFirat UniversityFirat University [1929]en_US
dc.description.sponsorshipThe authors would like to extend their thanks to Firat University for their financial support (project no: 1929).en_US
dc.identifier.doi10.1016/j.clinbiochem.2013.01.015en_US
dc.identifier.endpage830en_US
dc.identifier.issn0009-9120
dc.identifier.issue9en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage828en_US
dc.identifier.urihttps://doi.org/10.1016/j.clinbiochem.2013.01.015
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6102
dc.identifier.volume46en_US
dc.identifier.wosWOS:000319549100025en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofClinical Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHyperemesis gravidarumen_US
dc.subjectGhrelinen_US
dc.subjectObestatinen_US
dc.subjectLeptinen_US
dc.subjectNesfatin-1en_US
dc.titleGhrelins, obestatin, nesfatin-1 and leptin levels in pregnant women with and without hyperemesis gravidarumen_US
dc.typeArticleen_US

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