Relation of the Number of Parity to Left Ventricular Diastolic Function in Pregnancy

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dc.contributor.authorKeskin, Muhammed
dc.contributor.authorAvşar, Şahin
dc.contributor.authorHayıroğlu, Mert İlker
dc.contributor.authorKeskin, Taha
dc.contributor.authorBörklü, Edibe Betül
dc.contributor.authorKaya, Adnan
dc.contributor.authorKozan, Ömer
dc.date.accessioned2020-04-30T23:31:36Z
dc.date.available2020-04-30T23:31:36Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionGuvenc, Tolga Sinan/0000-0002-6738-266X; Keskin, Muhammed/0000-0002-4938-0097en_US
dc.descriptionWOS: 000405144700024en_US
dc.descriptionPubMed: 28479168en_US
dc.description.abstractLeft ventricular diastolic dysfunction (LVDD) has been relatively less studied than other cardiac changes during pregnancy. Previous studies revealed a mild diastolic deterioration during pregnancy. However, these studies did not evaluate the long-term effect of parity on left ventricular diastolic function. A comprehensive study evaluating the long-term effect of parity on diastolic function is required. A total of 710 women with various number of parity were evaluated through echocardiography to reveal the status of diastolic function. Echo cardiographic parameters were compared among the women by parity number and categorized accordingly: none, 0 to 4 and 4< parity (grand multiparous). In nulliparous group, 19 women (23.2%) had grade 1 LVDD, and only 2 women (2.4%) had grade 2 LVDD. In women with a parity number of 0 to 4, 209 women (38.3%) had grade 1 LVDD, and only 17 women (3.1%) had grade 2 LVDD. In grand multiparous group, only 2 women (2.4%) did not have LVDD, and 12 women (14.6%) had grade 2 LVDD. None of the subjects had grade 3 or grade 4 LVDD. According to hierarchical logistic regression analysis, any grade of LVDD and grade 2 LVDD had the highest rates at parity category of > 4 parity and that had 21 and 5.8 times higher than nulliparous group, respectively. In conclusion, according to the present study, grand multiparity but not multiparity, severely deteriorates left ventricular diastolic function. Further studies are warranted to evaluate the risk of gradual diastolic dysfunction after each pregnancy. (C) 2017 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.amjcard.2017.03.244en_US
dc.identifier.endpage159en_US
dc.identifier.issn0002-9149
dc.identifier.issn1879-1913
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage154en_US
dc.identifier.urihttps://doi.org/10.1016/j.amjcard.2017.03.244
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4345
dc.identifier.volume120en_US
dc.identifier.wosWOS:000405144700024en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherExcerpta Medica Inc-Elsevier Science Incen_US
dc.relation.ispartofAmerican Journal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleRelation of the Number of Parity to Left Ventricular Diastolic Function in Pregnancyen_US
dc.typeArticleen_US

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