Are serum eosinophilic cationic protein levels of toll collectors affected by diesel exhaust exposure?

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dc.contributor.authorBilgin, Cahit
dc.contributor.authorArbak, Peri Meram
dc.contributor.authorYavuz, Özlem
dc.contributor.authorBalbay, Ege Güleç
dc.contributor.authorBalbay, Öner Abidin
dc.contributor.authorAnnakkaya, Ali Nihat
dc.date.accessioned2020-04-30T22:39:37Z
dc.date.available2020-04-30T22:39:37Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionBalbay, Ege Gulec/0000-0002-1557-7019; Annakkaya, Ali Nihat N/0000-0002-7661-8830en_US
dc.descriptionWOS: 000389560100022en_US
dc.descriptionPubMed: 27882015en_US
dc.description.abstractObjective: There are few studies on the diesel exhaust particulates (DEP) / eosinophilic cationic protein (ECP) level relationship. This study aimed to detect ECP levels in a highly DE exposed group, named as toll collectors. Methods: In a cross-sectional study, levels of serum ECP, rates of respiratory symptoms, mean levels of respiratory functions, smoking status, and variations in peak expiratory flow (PEF) during weekends and working days were compared for 68 toll collectors (TC) (range of age, 24-48 years) and 28 controls (range of age, 25-61 years). All subjects in the study group were men. Results: No significant difference was observed in terms of symptoms and smoking rates between the toll collectors and control group. The number of toll collectors [12/68 (17.7%) vs 1/28 (3.5%)] with diurnal PEF variability in the working period was higher than that of controls (p=0.058). Mean ECP level of toll collectors was higher than that of controls (32.8 vs 21.4 ng/L), but the difference was not significant. Mean ECP levels were higher in subjects experiencing diurnal PEF variability during work and off-work periods (34.9 vs 28.3 ng/L, p=0.410). Conclusions: Serial PEF measurements combined with serum ECP measurements did not add a new tool to detect the sensitivity of workers dealing with DE. Much more diesel exhaust exposed workers should be included to search for cheap and available methods when evaluating airway.en_US
dc.identifier.doi10.12669/pjms.325.10844en_US
dc.identifier.endpage1173en_US
dc.identifier.issn1682-024X
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1169en_US
dc.identifier.urihttps://doi.org/10.12669/pjms.325.10844
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2782
dc.identifier.volume32en_US
dc.identifier.wosWOS:000389560100022en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherProfessional Medical Publicationsen_US
dc.relation.ispartofPakistan Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiesel exhausten_US
dc.subjectPulmonary functionen_US
dc.subjectPEF variabilityen_US
dc.subjectECPen_US
dc.subjectToll collectorsen_US
dc.titleAre serum eosinophilic cationic protein levels of toll collectors affected by diesel exhaust exposure?en_US
dc.typeArticleen_US

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