Are serum eosinophilic cationic protein levels of toll collectors affected by diesel exhaust exposure?
Yükleniyor...
Dosyalar
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Professional Medical Publications
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: There are few studies on the diesel exhaust particulates (DEP) / eosinophilic cationic protein (ECP) level relationship. This study aimed to detect ECP levels in a highly DE exposed group, named as toll collectors. Methods: In a cross-sectional study, levels of serum ECP, rates of respiratory symptoms, mean levels of respiratory functions, smoking status, and variations in peak expiratory flow (PEF) during weekends and working days were compared for 68 toll collectors (TC) (range of age, 24-48 years) and 28 controls (range of age, 25-61 years). All subjects in the study group were men. Results: No significant difference was observed in terms of symptoms and smoking rates between the toll collectors and control group. The number of toll collectors [12/68 (17.7%) vs 1/28 (3.5%)] with diurnal PEF variability in the working period was higher than that of controls (p=0.058). Mean ECP level of toll collectors was higher than that of controls (32.8 vs 21.4 ng/L), but the difference was not significant. Mean ECP levels were higher in subjects experiencing diurnal PEF variability during work and off-work periods (34.9 vs 28.3 ng/L, p=0.410). Conclusions: Serial PEF measurements combined with serum ECP measurements did not add a new tool to detect the sensitivity of workers dealing with DE. Much more diesel exhaust exposed workers should be included to search for cheap and available methods when evaluating airway.
Açıklama
Balbay, Ege Gulec/0000-0002-1557-7019; Annakkaya, Ali Nihat N/0000-0002-7661-8830
WOS: 000389560100022
PubMed: 27882015
WOS: 000389560100022
PubMed: 27882015
Anahtar Kelimeler
Diesel exhaust, Pulmonary function, PEF variability, ECP, Toll collectors
Kaynak
Pakistan Journal Of Medical Sciences
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
32
Sayı
5
