Free amino acid concentration in aqueous humour of patients with nuclear or cortical cataract

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dc.contributor.authorKeleş, Mevlüt Sait
dc.contributor.authorKeleş, Sadullah
dc.contributor.authorKulaçoğlu, Destan Nil
dc.contributor.authorTaysı, Seyithan
dc.contributor.authorBaykal, Orhan
dc.contributor.authorMemişoğulları, Ramazan
dc.contributor.authorŞahin, Yaşar Nuri
dc.date.accessioned2020-05-01T12:10:06Z
dc.date.available2020-05-01T12:10:06Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionTAYSI, Seyithan/0000-0003-1251-3148en_US
dc.descriptionWOS: 000291669500018en_US
dc.description.abstractAim: Since the free amino acids (a.a.) and derivated a.a. compounds in physiological fluids might reflect physiological or pathological conditions, some researchers have investigated the correlation of a.a. concentrations in physiological fluids with some clinical conditions, including ocular diseases. Here, we aimed to compare free and derivated a.a. in nuclear (generally a physiologic condition) and cortical (generally a pathologic condition) cataract. Materials and methods: Ten patients with nuclear and 10 with cortical cataract were included in this study. Aqueous humour a.a. and derivated a.a. compounds were determined by HPLC method (HP 1100) with Pickering post-column derivatization. Results: There was no significant difference between cortical and nuclear cataract groups in terms of aqueous humour total, glyco/ketogenic and standard a.a. contents, and nonessential (P < 0.01), glycogenic (P < 0.001) and ketogenic (P < 0.001) a.a. concentrations were found higher, and derivated (P < 0.001) a.a. concentrations were lower in the cortical cataract patients compared to the nuclear cataract patients. Conclusion: The present study suggests that there may be a difference between the nuclear and cortical cataract groups with respect to the contents of a.a. and derivated a.a. compounds in aqueous humour.en_US
dc.identifier.doi10.3906/sag-0805-32en_US
dc.identifier.endpage505en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage501en_US
dc.identifier.urihttps://doi.org/10.3906/sag-0805-32
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6008
dc.identifier.volume41en_US
dc.identifier.wosWOS:000291669500018en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCataracten_US
dc.subjectfree amino acidsen_US
dc.subjectaqueous humouren_US
dc.titleFree amino acid concentration in aqueous humour of patients with nuclear or cortical cataracten_US
dc.typeArticleen_US

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