Randomized Comparison of Efficacy of Paracetamol, Lornoxicam, and Tramadol Representing Three Different Groups of Analgesics for Pain Control in Extracorporeal Shockwave Lithotripsy

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dc.contributor.authorAkçalı, Gülgün Elif
dc.contributor.authorİskender, Abdülkadir
dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorKayıkçı, Ali
dc.contributor.authorYalçın, Gülbin Sezen
dc.contributor.authorÇam, Kamil
dc.contributor.authorBalcıoğlu, Yahya Okan
dc.date.accessioned2020-04-30T23:31:33Z
dc.date.available2020-04-30T23:31:33Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000277213300027en_US
dc.descriptionPubMed: 20184444en_US
dc.description.abstractPurpose: Extracorporeal shockwave lithotripsy (SWL) is the mainstay treatment modality for upper urinary tract stones. However, it is a relatively painful procedure and so an efficient analgesia is required for better clinical success. The ideal method of anesthesia has not been standardized. The objective of this randomized study, for the first time in the literature, was to compare the efficacy of three common analgesics, each belonging to a different group, in pain control during SWL. Patients and Methods: In this randomized controlled study, 90 patients with upper urinary tract stones undergoing SWL were randomly divided into three groups. Group I (n = 30) received 1 g of paracetamol, group II (n = 30) received 8 mg of lornoxicam, and group III (n = 30) had 1 mg/kg of tramadol. No premedication was applied in all groups. Pain scores by visual analog scale (VAS), blood pressure, heart rate, respiratory rate, and peripheral oxygen saturation were noted before procedure and at 1 minute and every 5 minutes during the SWL. Supplementary analgesic consumption was recorded. Moreover, all adverse effects and both patient and urologist satisfaction were documented. Results: Demographic parameters of the three groups were similar. All monitored parameters were also not different among the groups. The mean VAS scores at all measured times during SWL were below 4 except for two occasions, indicating a relatively efficient overall pain control provided by these three medications. Moreover, the mean VAS scores were similar among these three groups at all measured times during SWL except for those at 5 and 20 minutes at which groups III and II showed lesser pain control, respectively. No difference was observed in the amount of supplementary analgesia, which was required at higher voltages in a majority of patients. There was no significant difference in side effects. Conclusion: This study suggests that paracetamol, lornoxicam, and tramadol can be safely and efficiently preferred in pain control during SWL.en_US
dc.identifier.doi10.1089/end.2009.0483en_US
dc.identifier.endpage620en_US
dc.identifier.issn0892-7790
dc.identifier.issn1557-900X
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage615en_US
dc.identifier.urihttps://doi.org/10.1089/end.2009.0483
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4304
dc.identifier.volume24en_US
dc.identifier.wosWOS:000277213300027en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMary Ann Liebert, Incen_US
dc.relation.ispartofJournal Of Endourologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleRandomized Comparison of Efficacy of Paracetamol, Lornoxicam, and Tramadol Representing Three Different Groups of Analgesics for Pain Control in Extracorporeal Shockwave Lithotripsyen_US
dc.typeArticleen_US

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