Effect of anesthesiological strategies on neonatal bilirubin levels during cesarean section: a prospective and randomized trial

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dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorAlbayrak, Mustafa
dc.contributor.authorŞeker, İlknur Suidiye
dc.contributor.authorKaynak, Gürsel
dc.contributor.authorİskender, Abdülkadir
dc.contributor.authorSezen, Gülbin Yalçın
dc.contributor.authorÖzdemir, İsmail
dc.date.accessioned2020-05-01T09:11:35Z
dc.date.available2020-05-01T09:11:35Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionYorulmaz, Ilknur Suidiye/0000-0002-1441-6360en_US
dc.descriptionWOS: 000295737300002en_US
dc.descriptionPubMed: 21136268en_US
dc.description.abstractPurpose Neonatal jaundice, a frequent problem in neonatology, can be influenced by many factors. Here, we sought to clarify the role of anesthesia and to compare the effects of various anesthesiological strategies on neonatal bilirubin levels during cesarean section. Methods We prospectively enrolled 167 ASA I-II status uncomplicated pregnant women who delivered by cesarean section as the study group. The patients were randomized based on anesthesiological strategy: inhalation (IA), spinal (SA), total intravenous (TIVA), and epidural anesthesia (EA) groups. Neonatal total (TB) and direct bilirubin (DB) levels at the 24th hour and 5th day of life and the need for phototherapy were compared between the groups. Results Direct bilirubin levels at 24th hour of SA group and EA group were higher compared to IA group (p = 0.008). When DB levels at fifth day were compared, levels in group TIVA were significantly higher than group SA (p = 0.019). TB levels at fifth day in group TIVA were higher than SA and EA groups (p = 0.05). The percentage of newborns needing phototherapy did not differ significantly among groups, but was highest in the TIVA group (25%), followed by the IA (15%), EA (10%) and SA (7%) groups (p = 0.08). Conclusions EA and SA at cesarean section seem to be better among the four anesthesia techniques considering neonatal hyperbilirubinemia. Our findings are consistent with the idea that anesthesia may be a risk factor for hyperbilirubinemia. Although anesthesia may not significantly increase the need for interventions such as phototherapy, it may increase the burden of time, labor and cost.en_US
dc.identifier.doi10.1007/s00404-010-1783-8en_US
dc.identifier.endpage1065en_US
dc.identifier.issn0932-0067
dc.identifier.issn1432-0711
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1059en_US
dc.identifier.urihttps://doi.org/10.1007/s00404-010-1783-8
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5678
dc.identifier.volume284en_US
dc.identifier.wosWOS:000295737300002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofArchives Of Gynecology And Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnesthesia techniqueen_US
dc.subjectNeonatal jaundiceen_US
dc.subjectCesarean sectionen_US
dc.titleEffect of anesthesiological strategies on neonatal bilirubin levels during cesarean section: a prospective and randomized trialen_US
dc.typeArticleen_US

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