Development of a quality of life scale specific for patients with benign prostatic hyperplasia

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dc.contributor.authorÇam, Kamil
dc.contributor.authorMüezzinoğlu, Talha
dc.contributor.authorAydemir, Ömer
dc.contributor.authorBüyükalpelli, Recep
dc.contributor.authorToktaş, Gökhan
dc.contributor.authorGemalmaz, Hakan
dc.date.accessioned2020-05-01T09:11:24Z
dc.date.available2020-05-01T09:11:24Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000316333600007en_US
dc.descriptionPubMed: 23420093en_US
dc.description.abstractThe improvement of quality of life (QoL) should be the major concern in any proposed treatment modality for any disorder. The objective of this study was to develop a new easy to use benign prostatic hyperplasia (BPH)-specific QoL scale that may guide the treatment policy in BPH. A total of 118 items addressing BPH-specific QoL were produced. After an elimination process, a 20-question scale was developed. This new scale, Short Form (SF)-36 and International Prostate Symptom Score (IPSS), was then administered to 50 healthy men (control group), and 108 BPH patients who received medical or surgical treatment. Reliability assessment consisted of internal consistency evaluation by the Cronbach's alpha reliability test. In construct validity, factor analysis was performed using principal component analysis with Varimax rotation. Response to change of this new form was also evaluated. Cronbach's alpha coefficient of this scale was found to be 0.8464. Item-total correlation coefficients were between 0.3298 and 0.7886 (p < 0.0001). Factor analysis for construct validity revealed four factors. The correlation coefficients were found to be r = 0.801 (p < 0.0001) with the total IPSS, and this new QoL scale had a relatively sufficient correlation with all domains of the SF-36. Moreover, a QoL score obtained by the summation of individual grades of each item may provide valuable information just like total IPSS. The mean QoL score was 4.96 +/- A 9.58 and 20.28 +/- A 9.14 in controls and BPH patients, respectively (p < 0.0001). Moreover, QoL score significantly improved by both medical and surgical treatment. The new BPH-specific QoL was shown to be reliable and valid.en_US
dc.identifier.doi10.1007/s11255-013-0384-4en_US
dc.identifier.endpage346en_US
dc.identifier.issn0301-1623
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage339en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-013-0384-4
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5564
dc.identifier.volume45en_US
dc.identifier.wosWOS:000316333600007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology And Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBenign prostatic hyperplasiaen_US
dc.subjectProstateen_US
dc.subjectQuality of lifeen_US
dc.subjectReliabilityen_US
dc.subjectValidityen_US
dc.titleDevelopment of a quality of life scale specific for patients with benign prostatic hyperplasiaen_US
dc.typeArticleen_US

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