Detection of cisplatin-induced ototoxicity with transient evoked otoacoustic emission test before pure tone audiometer

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dc.contributor.authorYılmaz, Süleyman
dc.contributor.authorÖktem, Fatih
dc.contributor.authorKaraman, Emin
dc.date.accessioned2020-05-01T09:11:19Z
dc.date.available2020-05-01T09:11:19Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000277939700006en_US
dc.descriptionPubMed: 19946777en_US
dc.description.abstractOur aim was to investigate cisplatin ototoxicity with transient evoked otoacoustic emission (TEOAE) test before it is seen with pure tone audiometer. In our study, we compared the hearing of the patients who are receiving 100 mg/m(2) 4-cycle cisplatin for lung cancer, with pure tone audiometer and transient evoked otoacoustic emission test in 1,000, 2,000 and 4,000 Hz. We found 55% hearing decrease with pure tone audiometer in patients that are receiving 100 mg/m(2) 4-cycle cisplatin for lung cancer. We also established emission amplitude decrease with TEOAE test in 85% of the patients. When we compare the patients' pure tone audiometer in 1,000, 2,000 and 4,000 Hz and TEOAE amplitude changes we did not find statistically significant results (P > 0.05), but when we compare the patients' TEOAE amplitude changes in 1,000, 2,000 and 4,000 Hz with control group we found statistically significant results (P < 0.05). Our results show that cisplatin ototoxicity could be find out with TEOAE test before it is seen with pure tone audiometer.en_US
dc.identifier.doi10.1007/s00405-009-1165-7en_US
dc.identifier.endpage1044en_US
dc.identifier.issn0937-4477
dc.identifier.issue7en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1041en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-009-1165-7
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5503
dc.identifier.volume267en_US
dc.identifier.wosWOS:000277939700006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives Of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCisplatinen_US
dc.subjectPure tone audiometeren_US
dc.subjectTransient evoked otoacoustic emissionen_US
dc.titleDetection of cisplatin-induced ototoxicity with transient evoked otoacoustic emission test before pure tone audiometeren_US
dc.typeArticleen_US

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