Evaluation of Paraoxonase Activity, Total Sialic Acid and Oxidative Stress in Sheep with Ecthyma Contagiosa

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dc.contributor.authorDeveci, Hacı Ahmet
dc.contributor.authorKükürt, Abdulsamed
dc.contributor.authorUzlu, Erdoğan
dc.contributor.authorSözdutmaz, İbrahim
dc.contributor.authorMerhan, Oğuz
dc.contributor.authorAktaş, Sinan
dc.contributor.authorKarapehlivan, Mahmut
dc.date.accessioned2020-05-01T12:14:52Z
dc.date.available2020-05-01T12:14:52Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionDEVECI, HACI AHMET/0000-0002-5613-0520; sozdutmaz, ibrahim/0000-0002-3712-7991en_US
dc.descriptionWOS: 000399881500016en_US
dc.description.abstractZoonoses are defined by the world health organization as diseases and infections which are transmitted naturally between vertebrate animals and human. Undestanding the zoonotic risk posed by pox viruses in companion animals is important for both human and animal health. contagious ecthyma is highly contagious, zoonotic, viral skin disease that affects sheep, goats and some other domesticated and wild animals. In this present study was detected and evaluated levels of plasma paraoxonase activity (PON1), high-density lipoprotein (HDL), total sialic acid (TSA), malondialdehyde (MDA), nitric oxide (NO) and total blood glutathione (GSH) concentrations in healthy sheep and natural infected sheeps with ecthyma. In healthy sheep, laboratory results were determined as PON1 218.54 +/- 17.93 U/L, TSA 59.89 +/- 5.59 mg/dL, HDL 48.4 +/- 4.88 mg/dL, MDA 8.58 +/- 0.80 mu mol/L, NO 7.78 +/- 1.02 mu mol/L and GSH 21.11 +/- 3.70 mg/dL. These values were found 174.92 +/- 18.68 U/L, 70.1 +/- 6.56 mg/dL, 37.9 +/- 6.47 mg/dL, 11.26 +/- 1.06 mu mol/L, 12.44 +/- 1.90 mu mol/L, 7.79 +/- 0.90 mg/dL respectively in sheeps wich are infected by ecthyma. As a result, it was concluded that there is oxidative stress due to imbalance between pro-oxidant and antioxidant molecules in sheep which are infected by ecthyma, and this imbalance is shaped by increasing oxidant levels.en_US
dc.identifier.doi10.9775/kvfd.2016.17001en_US
dc.identifier.endpage457en_US
dc.identifier.issn1300-6045
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage453en_US
dc.identifier.urihttps://doi.org/10.9775/kvfd.2016.17001
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6373
dc.identifier.volume23en_US
dc.identifier.wosWOS:000399881500016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEcthymaen_US
dc.subjectParaoxonase activityen_US
dc.subjectTotal sialic aciden_US
dc.subjectOxidative stressen_US
dc.subjectSheepen_US
dc.titleEvaluation of Paraoxonase Activity, Total Sialic Acid and Oxidative Stress in Sheep with Ecthyma Contagiosaen_US
dc.typeArticleen_US

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