Total atrial conduction time evaluated with tissue Doppler imaging increases in hypertensive patients with hyperuricemia
Yükleniyor...
Dosyalar
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
BackgroundSerum uric acid (SUA) is an independent predictor of cardiovascular events in patients with hypertension. Total atrial conduction time (TACT) is a novel echocardiographic parameter used to identify the presence of electrical and structural atrial remodeling. We hypothesized that elevated SUA levels may be associated with prolonged TACT.MethodsA total of 50 consecutive hyperuricemic (defined as SUA>7mg/dl for men and >6.0mg/dl for women) patients who had hypertension were included in the study. A total of 42 normouricemic patients were also recruited consecutively as the control group. All patients were evaluated by two-dimensional echocardiography and TACT was estimated by measuring the time delay between the onset of the P-wave of ECG and peak A'-wave on the tissue Doppler imaging (TDI) of the left atrial lateral wall (PA-TDI duration).ResultsThere were no significant differences between the two groups according to age, sex, left ventricular systolic function, left atrial diameter, and systolic and diastolic blood pressure values. PA-TDI duration was found to be significantly increased in the hyperuricemic group (112.314.7 vs. 92 +/- 12.7ms; P<0.001) and positively correlated with the mean value of SUA levels (r=0.48, P<0.001).ConclusionTACT increases in patients with hyperuricemia. Certainly, larger studies in different populations should further examine this potential association.
Açıklama
WOS: 000361477800003
PubMed: 25968094
PubMed: 25968094
Anahtar Kelimeler
atrial conduction time, atrial fibrillation, hypertension, tissue Doppler echocardiography, uric acid
Kaynak
Blood Pressure Monitoring
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
20
Sayı
5
