Is unexplained elevated maternal serum alpha-fetoprotein still important predictor for adverse pregnancy outcome?

dc.contributor.authorBaşbuğ, Derya
dc.contributor.authorBaşbuğ, Alper
dc.contributor.authorGülerman, Cavidan
dc.date.accessioned2020-04-30T23:18:47Z
dc.date.available2020-04-30T23:18:47Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000405108100009en_US
dc.descriptionPubMed: 28727133en_US
dc.description.abstractObjectives: The purpose of this study was to determined the predictive value of maternal serum alpha-fetoprotein (MSAFP) as a marker for adverse pregnancy outcomes. Material and methods: This study was carried out at Dr. Zekai Tahir Burak Women's Health Education and Research Hospital between 2009 and 2010. This study included a total of 1,177 pregnant women, including 170 in the study group and 1,007 in the control group. Pregnancy outcomes and characteristics were analyzed with regard to the MSAFP value. Results: Gestational week, birth weight and APGAR scores were significantly lower in the elevated MSAFP group (p < 0.001). Adverse pregnancy outcomes, such as preterm delivery, preterm premature rupture of membranes (PPROM), oligohydramnios and intrauterine growth restriction (IUGR) rates were increased in the elevated MSAFP group. Conclusions: Although ultrasound outweighs as a screening method for neural tube defects and non-invasive prenatal testing outweighs for aneuploidy screening MSAFP level in the second trimester is still an important predictor for poor maternal/fetal outcomes.en_US
dc.identifier.doi10.5603/GP.a2017.0061en_US
dc.identifier.endpage330en_US
dc.identifier.issn0017-0011
dc.identifier.issn2543-6767
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage325en_US
dc.identifier.urihttps://doi.org/10.5603/GP.a2017.0061
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3521
dc.identifier.volume88en_US
dc.identifier.wosWOS:000405108100009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofGinekologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectalpha-fetoproteinen_US
dc.subjectadverse pregnancy outcomeen_US
dc.subjectprenatal testsen_US
dc.titleIs unexplained elevated maternal serum alpha-fetoprotein still important predictor for adverse pregnancy outcome?en_US
dc.typeArticleen_US

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