Evaluation of Clinical Features and Treatment Results of Pediatric Patients With Pre-Diagnosis of COVID-19

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dc.authorscopusid35424415800
dc.authorscopusid57208314562
dc.authorscopusid56815156200
dc.authorscopusid8709583700
dc.contributor.authorSav, Nadide Melike
dc.contributor.authorTüray, S.
dc.contributor.authorÖzde, Ş.
dc.contributor.authorÖksüz, Ş.
dc.date.accessioned2023-07-26T11:54:34Z
dc.date.available2023-07-26T11:54:34Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractAim: The epidemiological characteristics and modes of transmission of coronavirus disease 2019 (COVID-19) in children are not yet fully understood. In this study, it was aimed to evaluate clinical, laboratory, and radiological findings and treatment approaches in patients with negative and positive PCR tests among those with suspected COVID-19 retrospectively. Material and Methods: This study was conducted with 317 patients under 18 years of age, who received outpatient or inpatient treatment with a pre-diagnosis of COVID-19. All patients were assessed for clinical course, disease severity, comorbidity, demographic characteristics, laboratory and radiodiagnostic tests, treatment characteristics, and outcomes. Results: The PCR test was positive in 133 (42%) and negative in 184 (58%) of the patients with suspected COVID-19. There was a history of contact in 78 (58.6%) and 51 (27.7%) of the PCR-positive and negative patients, respectively (p<0.001). While the PCR-negative group had a higher rate of hospitalization (p=0.020), hospital stay was longer in PCR-positive cases (p=0.037). The white blood cell count (p=0.001), platelet count (p=0.037), neutrophil count (p=0.015), and lactate level (p=0.025) were significantly lower in the PCR-positive group. Conclusion: Early detection and isolation of children with symptoms suggestive of COVID-19 are important to limit the spread of the disease. It can be challenging initially to clinically understand whether the case has COVID-19, especially in pediatric patients. PCR test is the gold standard in the diagnosis of COVID-19. Considering the prevalence, severity, and complications of the outbreak, it would be a proper approach to initially evaluate suspected patients as COVID-19 patients. © 2022, Duzce University Medical School. All rights reserved.en_US
dc.identifier.doi10.18678/dtfd.1098928
dc.identifier.endpage169en_US
dc.identifier.issn1307-671X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85136420985en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage162en_US
dc.identifier.trdizinid1115673en_US
dc.identifier.urihttps://doi.org/10.18678/dtfd.1098928
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1115673
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12870
dc.identifier.volume24en_US
dc.identifier.wosWOS:001207163500013en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorSav, Nadide Melike
dc.institutionauthorTüray, S.
dc.institutionauthorÖzde, Ş.
dc.institutionauthorÖksüz, Ş.
dc.language.isoenen_US
dc.publisherDuzce University Medical Schoolen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectchildhooden_US
dc.subjectCOVID-19en_US
dc.subjectSARS-CoV-2en_US
dc.titleEvaluation of Clinical Features and Treatment Results of Pediatric Patients With Pre-Diagnosis of COVID-19en_US
dc.title.alternativeCOVID-19 Ön Tanısı Olan Çocuk Hastaların Klinik Özellikleri ile Tedavi Sonuçlarının Değerlendirilmesien_US
dc.typeArticleen_US

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