Combined periprostatic and intraprostatic local anesthesia for prostate biopsy: A double-blind, placebo controlled, randomized trial

dc.contributor.authorÇam, Kamil
dc.contributor.authorŞener, Murat
dc.contributor.authorKayıkçı, Ali
dc.contributor.authorAkman, Yavuz
dc.contributor.authorErol, Ali
dc.date.accessioned2020-04-30T22:41:01Z
dc.date.available2020-04-30T22:41:01Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000256643900032en_US
dc.descriptionPubMed: 18485414en_US
dc.description.abstractPurpose: Transrectal ultrasonography guided prostate biopsy is the principle procedure in the histological diagnosis of prostate cancer. Recently a trend toward increasing the number of cores has been popularized. This practice further increases the need for a proper anesthetic application. However, there is no consensus on a standard local anesthetic strategy, while groups at most institutions currently prefer periprostatic anesthesia. We prospectively evaluated the contribution of intraprostatic anesthesia for transrectal prostate biopsies even when the sampling number was doubled to 12 cores. Materials and Methods: A total of 200 patients who underwent prostate biopsy with transrectal ultrasound guidance were included. The 2 groups received the usual periprostatic anesthesia. Consequently patients were prospectively randomized into 2 groups. Group 1 received additional intraprostatic lidocaine injection, while group 2 received the same amount of injection of 0.9% NaCl. The efficiency of applied local anesthesia was assessed by a visual analog pain scale. Results: The study groups were comparable regarding patient age, prostate size and cancer rate. Pain scores revealed that the combination of intraprostatic and periprostatic local anesthesia provided significantly better pain control than periprostatic infiltration alone. No difference was observed regarding the morbidity rate in the 2 groups. Conclusions: The current study suggested that adding intraprostatic local anesthesia provides a significantly efficient strategy during transrectal ultrasound prostate biopsy, even in cases of 12-core sampling. Subsequent trials are needed to establish a standard analgesia policy for prostate biopsy.en_US
dc.identifier.doi10.1016/j.juro.2008.03.052en_US
dc.identifier.endpage144en_US
dc.identifier.issn0022-5347
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage141en_US
dc.identifier.urihttps://doi.org/10.1016/j.juro.2008.03.052
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3107
dc.identifier.volume180en_US
dc.identifier.wosWOS:000256643900032en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofJournal Of Urologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectprostateen_US
dc.subjectbiopsyen_US
dc.subjecttransrectal ultrasonographyen_US
dc.subjectanesthesiaen_US
dc.subjectpainen_US
dc.titleCombined periprostatic and intraprostatic local anesthesia for prostate biopsy: A double-blind, placebo controlled, randomized trialen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
3107.pdf
Boyut:
71.57 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text