Serum Levels of Omentin in Pseudoexfoliation Syndrome
dc.contributor.author | Bucak, Yasin Y. | |
dc.contributor.author | Tosun, Mehmet | |
dc.contributor.author | Simavlı, Hüseyin | |
dc.contributor.author | Önder, Halil İbrahim | |
dc.contributor.author | Erdurmuş, Mesut | |
dc.date.accessioned | 2020-04-30T23:31:52Z | |
dc.date.available | 2020-04-30T23:31:52Z | |
dc.date.issued | 2016 | |
dc.department | DÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.description | Simavli, Huseyin/0000-0003-1657-9099 | en_US |
dc.description | WOS: 000374819800014 | en_US |
dc.description | PubMed: 25264991 | en_US |
dc.description.abstract | Purpose: Omentin, a member of the adipocytokines family, is derived from adipose tissue and a lower level of serum omentin is considered as a metabolic risk factor. The aim of the present study is to evaluate the serum levels of omentin in patients with pseudoexfoliation syndrome (PES). Materials and Methods: Patients without any systemic or ocular disease other than PES were included in the study. Age-matched and sex-matched healthy volunteers without PES were accepted as a control group. After detailed ophthalmologic examination, blood samples were obtained from a forearm vein. Serum levels of omentin were determined by the method of enzyme-linked immunosorbent assay. Results: The mean age of the PES group (12 females, 12 males, n = 24) was 75.2 +/- 8.4 years, and the control group (10 females, 10 males, n = 20) was 75 +/- 6.7 years. There was no difference between the groups in terms of age (P = 0.93) and sex (P = 0.9). The mean serum levels of omentin in the PES group were 801.5 +/- 317.1 ng/mL and in the control group were 1150.1 +/- 584.1 ng/mL. The mean serum omentin levels were significantly lower in patients with PES (P = 0.016). Conclusion: Lower levels of serum omentin in patients with PES compared with healthy subjects may support the theory of systemic nature of the disease. | en_US |
dc.identifier.doi | 10.1097/IJG.0000000000000139 | en_US |
dc.identifier.endpage | 148 | en_US |
dc.identifier.issn | 1057-0829 | |
dc.identifier.issn | 1536-481X | |
dc.identifier.issue | 2 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 145 | en_US |
dc.identifier.uri | https://doi.org/10.1097/IJG.0000000000000139 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12684/4513 | |
dc.identifier.volume | 25 | en_US |
dc.identifier.wos | WOS:000374819800014 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.language.iso | en | en_US |
dc.publisher | Lippincott Williams & Wilkins | en_US |
dc.relation.ispartof | Journal Of Glaucoma | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | pseudoexfoliation syndrome | en_US |
dc.subject | omentin | en_US |
dc.subject | body mass index | en_US |
dc.title | Serum Levels of Omentin in Pseudoexfoliation Syndrome | en_US |
dc.type | Article | en_US |
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