Oxytocin versus sustained-release dinoprostone vaginal pessary for labor induction of unfavorable cervix with Bishop score >= 4 and >= 6: A randomized controlled trial

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dc.contributor.authorKoç, Önder
dc.contributor.authorDuran, Bülent
dc.contributor.authorÖzdemirci, Şafak
dc.contributor.authorAlbayrak, Mustafa
dc.contributor.authorKoç, Ümmügülsüm
dc.date.accessioned2020-04-30T23:20:28Z
dc.date.available2020-04-30T23:20:28Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000317307400006en_US
dc.descriptionPubMed: 23167718en_US
dc.description.abstractAim To compare the efficacy and safety of high-dose intravenous oxytocin and sustained-release dinoprostone vaginal pessaries for cervical ripening and labor induction in pregnant patients at term with poor Bishop scores. Material and Methods Women at term with a Bishop score 4 and 6 were randomized into two groups to undergo induction of labor with either high-dose oxytocin administered intravenously (n=90) or dinoprostone-only vaginal pessary without oxytocin augmentation (n=90). The main outcome measures were rate of cesarean delivery, induction to delivery interval, number of deliveries achieved within 4, 8, 12, and 16h of labor induction, maternal complications during induction, fetal outcome, and total hospital stay. In this study, per-protocol analysis was performed. Results There were fewer cesarean deliveries with oxytocin compared to dinoprostone-only groups (7/79 vs 14/89); however, the difference was not statistically significant. The inductiondelivery intervals (7.9h vs 12.0h, P<0.001; and 5.7 vs 10.4h, P<0.001; oxytocin vs dinoprostone-only for primiparous and multiparous patients, respectively) were significantly shorter in oxytocin-induced patients compared to dinoprostone-only. A significantly higher percentage of patients delivered in the oxytocin group compared to the dinoprostone-only group in 4, 8, 12, 16, and 20h. Conclusion Intravenous oxytocin is effective to stimulate labor at term for patients with Bishop scores 4 and 6, with a shorter time interval from induction to vaginal delivery.en_US
dc.identifier.doi10.1111/j.1447-0756.2012.02045.xen_US
dc.identifier.endpage798en_US
dc.identifier.issn1341-8076
dc.identifier.issn1447-0756
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage790en_US
dc.identifier.urihttps://doi.org/10.1111/j.1447-0756.2012.02045.x
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4012
dc.identifier.volume39en_US
dc.identifier.wosWOS:000317307400006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Obstetrics And Gynaecology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdinoprostoneen_US
dc.subjectlabor inductionen_US
dc.subjectoxytocinen_US
dc.subjectrandomized controlled trialen_US
dc.titleOxytocin versus sustained-release dinoprostone vaginal pessary for labor induction of unfavorable cervix with Bishop score >= 4 and >= 6: A randomized controlled trialen_US
dc.typeArticleen_US

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