Relationship of maternal serum resistin and visfatin levels with gestational diabetes mellitus

Basit Öğe Kaydı
dc.contributor.authorKarataş, Ahmet
dc.contributor.authorIşıkkent, Nilüfer Tuncay
dc.contributor.authorÖzlü, Tülay
dc.contributor.authorDemirin, Hilmi
dc.date.accessioned2020-04-30T23:31:37Z
dc.date.available2020-04-30T23:31:37Z
dc.date.issued2014
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000334743400007en_US
dc.descriptionPubMed: 24512558en_US
dc.description.abstractIntroduction: Adiponectin, resistin and visfatin are thought to play role in the pathophysiology of gestational diabetes (GDM). In this study, we aimed to investigate the association of maternal second trimester serum resistin and visfatin levels with GDM. Materials and methods: Screening and diagnosis for GDM was performed between the 24-28th gestational weeks. About 40 women diagnosed with GDM and 40 non-diabetic women constituted the study and control groups, respectively. Groups were compared for second trimester maternal serum resistin, visfatin and HbA1c levels, HOMA-IR and postpartum 75 g OGTT results. Results: Mean serum resistin (p = 0.071) and visfatin (p = 0.194) levels were similar between the groups. However, mean BMI (p = 0.013), HOMA-IR (p = 0.019), HbA1c (p<0.0001) and birth weight (p = 0.037) were significantly higher in GDM group compared to controls. Type 2 diabetes and impaired glucose tolerance were detected in 2 (5%) and 7 (20%) women in the GDM group, respectively, with 75 g OGTT performed at the postpartum 6th week. Resistin levels of patients with GDM and postpartum glucose intolerance were higher than those with GDM but no postpartum glucose intolerance (p = 0.012). Visfatin levels in the GDM group showed a positive correlation with biparietal diameter, head circumference, abdominal circumference and femur length (p<0.05). Conclusion: Maternal serum resistin and visfatin levels are unchanged in GDM. In patients with GDM, second trimester resistin levels may be predictive for postpartum glucose intolerance and second trimester visfatin levels may be related with fetal biometric measurements. Further larger studies are needed.en_US
dc.description.sponsorshipDuzce University, Medical Faculty Scientific Study Research CommissionDuzce University [2012.04.HD.060]en_US
dc.description.sponsorshipThe authors report no declarations of interest. This study was financially endorsed by Duzce University, Medical Faculty Scientific Study Research Commission (registration number 2012.04.HD.060).en_US
dc.identifier.doi10.3109/09513590.2014.887670en_US
dc.identifier.endpage358en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage355en_US
dc.identifier.urihttps://doi.org/10.3109/09513590.2014.887670
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4365
dc.identifier.volume30en_US
dc.identifier.wosWOS:000334743400007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGestational diabetesen_US
dc.subjectinsulin resistanceen_US
dc.subjectresistinen_US
dc.subjectvisfatinen_US
dc.titleRelationship of maternal serum resistin and visfatin levels with gestational diabetes mellitusen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
4365.pdf
Boyut:
183.96 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu