Dual oocyte retrieval and embryo transfer in the same cycle for women with premature ovarian insufficiency

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dc.contributor.authorHatırnaz, Şafak
dc.contributor.authorAta, Barış
dc.contributor.authorHatırnaz, Ebru
dc.contributor.authorBaşbuğ, Alper
dc.contributor.authorTannus, Samer
dc.date.accessioned2020-05-01T09:11:31Z
dc.date.available2020-05-01T09:11:31Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionHatirnaz, Safak/0000-0001-8859-0639en_US
dc.descriptionWOS: 000460964200005en_US
dc.descriptionPubMed: 30690724en_US
dc.description.abstractObjective To compare dual oocyte retrieval with minimal ovarian stimulation and embryo transfer in the same menstrual cycle versus conventional ovarian stimulation among women with premature ovarian insufficiency (POI). Methods A retrospective study of 51 women with POI attending a reproductive center in Turkey between 2013 and 2015. Women with an ovarian follicle of 12 mm or larger early in the follicular phase who underwent oocyte retrieval followed by an immediate cycle of ovarian stimulation (group 1, n=14) were compared with those who received conventional ovarian stimulation (group 2, n=37). Both groups underwent subsequent ovarian stimulation cycles to obtain optimally two embryos for transfer. Results The groups had similar baseline parameters. Serum estradiol was higher in group 1 (P<0.001); total number of oocyte retrievals was higher in group 2 (P<0.001); and total number of oocytes retrieved was similar (P=0.192). Group 1 had more higher-quality embryos (P=0.031). There was a non-significant trend toward higher live birth rates in the dual trigger group (28% vs 8%, P=0.08). Conclusion Rescuing growing follicles early in the follicular phase combined with subsequent ovarian stimulation and embryo transfer in the same cycle resulted in fewer oocyte retrieval cycles and might potentially improve reproductive outcomes.en_US
dc.identifier.doi10.1002/ijgo.12768en_US
dc.identifier.endpage27en_US
dc.identifier.issn0020-7292
dc.identifier.issn1879-3479
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage23en_US
dc.identifier.urihttps://doi.org/10.1002/ijgo.12768
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5639
dc.identifier.volume145en_US
dc.identifier.wosWOS:000460964200005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Gynecology & Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDual oocyte retrievalen_US
dc.subjectFollicular wavesen_US
dc.subjectOvarian stimulationen_US
dc.subjectPremature ovarian insufficiencyen_US
dc.subjectRandom starten_US
dc.titleDual oocyte retrieval and embryo transfer in the same cycle for women with premature ovarian insufficiencyen_US
dc.typeArticleen_US

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