Cut-Off Values For EEG Frequency in Differentiation of Alzheimer, Non-Alzheimer Dementia and Healthy Subjects: An Application of 3D-ROC Surface Method

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dc.contributor.authorAnkaralı, Handan
dc.contributor.authorAnkaralı, Seyit
dc.contributor.authorGökce, Fatih Mehmet
dc.contributor.authorDemir, Şerif
dc.contributor.authorKeçeci, Hulusi
dc.date.accessioned2020-05-01T09:11:16Z
dc.date.available2020-05-01T09:11:16Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionAnkarali, Handan Camdeviren/0000-0002-3613-0523; Ankarali, Seyit/0000-0003-3752-0846en_US
dc.descriptionWOS: 000284492700013en_US
dc.description.abstractObjectives: To write a new macro programme for the use of the non-parametric 3-D Receiver Operating Characteristic (ROC) surface method in the discrimination of three or more groups, to study the usefulness of electroencephalography (EEG) frequency in the diagnosis of Alzheimer type dementia (AD), non-Alzheimer type dementia (NAD) and healthy subjects, and to determine cut-off values of EEG frequency. Patients and Methods: The mean EEG frequencies in the left fontal region EEG records of subjects in the present study were calculated and the ROC surface method was used in discrimination of the groups. Results: The volume under the ROC surface was calculated as 0.464+/-0.150. Accuracy of the mean frequency in differentiation of groups was statistically significant (p=0.024). 8 Hz was found to be convenient for differentiation of AD from NAD patients and 10 Hz for the differentiation of NAD patients and healthy subjects. The sensitivity was 87.5% for Alzheimer's dementia diagnosis and total accuracy was 65% using this cut-off pair. Conclusion: We suggest that the mean EEG frequency may be used only as a pre-diagnostic tool for the differential diagnosis of these groups.en_US
dc.identifier.doi10.5174/tutfd.2009.01528.2en_US
dc.identifier.endpage286en_US
dc.identifier.issn1301-3149
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage281en_US
dc.identifier.urihttps://doi.org/10.5174/tutfd.2009.01528.2
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5443
dc.identifier.volume27en_US
dc.identifier.wosWOS:000284492700013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherEkin Tibbi Yayincilik Ltd Sti-Ekin Medical Publen_US
dc.relation.ispartofTrakya Universitesi Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlzheimer type dementiaen_US
dc.subjectdementiaen_US
dc.subjectelectroencephalographyen_US
dc.subjectdiagnostic accuracyen_US
dc.subjectvolume under a ROC surfaceen_US
dc.subjectclassificationen_US
dc.titleCut-Off Values For EEG Frequency in Differentiation of Alzheimer, Non-Alzheimer Dementia and Healthy Subjects: An Application of 3D-ROC Surface Methoden_US
dc.typeArticleen_US

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