The effects of ultrafiltration and diuretic therapies on oxidative stress markers in patients with cardio-renal syndrome

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dc.contributor.authorSav, Tansu
dc.contributor.authorÇeçen, Faruk
dc.contributor.authorAlbayrak, Enver Sinan
dc.date.accessioned2020-04-30T23:33:33Z
dc.date.available2020-04-30T23:33:33Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000406380900012en_US
dc.descriptionPubMed: 27097156en_US
dc.description.abstractBACKGROUND: Cardiorenal syndrome (CRS) is defined as complex pathophysiological disorder of the heart and kidneys. Both heart and renal failure are characterized by increased systemic oxidative stress in CRS. The aim of the present study is to assess the impacts of ultrafiltration (UF) and furosemide treatment on oxidative stress markers and renal functions in patients with CRS. METHODS: In the study 77 patients with CRS (37 patients in the UF group and 40 patients in the furosemide group) were included. Plasma superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) levels were studied in all patients on admission and at the end of the study. RESULTS: Plasma SOD, CAT, MDA and GSH-Px levels did not show significant difference between the groups. CONCLUSIONS: The effects of UF and furosemide therapies were similar on oxidative stress markers in patients with CRS. These methods safely decrease volume overload in a short-term period.en_US
dc.identifier.doi10.23736/S0393-2249.16.02663-1en_US
dc.identifier.endpage407en_US
dc.identifier.issn0393-2249
dc.identifier.issn1827-1758
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage400en_US
dc.identifier.urihttps://doi.org/10.23736/S0393-2249.16.02663-1
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4994
dc.identifier.volume69en_US
dc.identifier.wosWOS:000406380900012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofMinerva Urologica E Nefrologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardioen_US
dc.subjectrenal syndromeen_US
dc.subjectOxidative stressen_US
dc.subjectRenal insufficiencyen_US
dc.subjectUltrafiltrationen_US
dc.titleThe effects of ultrafiltration and diuretic therapies on oxidative stress markers in patients with cardio-renal syndromeen_US
dc.typeArticleen_US

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