The effects of ultrafiltration and diuretic therapies on oxidative stress markers in patients with cardio-renal syndrome
Loading...
Files
Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
Edizioni Minerva Medica
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
BACKGROUND: Cardiorenal syndrome (CRS) is defined as complex pathophysiological disorder of the heart and kidneys. Both heart and renal failure are characterized by increased systemic oxidative stress in CRS. The aim of the present study is to assess the impacts of ultrafiltration (UF) and furosemide treatment on oxidative stress markers and renal functions in patients with CRS. METHODS: In the study 77 patients with CRS (37 patients in the UF group and 40 patients in the furosemide group) were included. Plasma superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) levels were studied in all patients on admission and at the end of the study. RESULTS: Plasma SOD, CAT, MDA and GSH-Px levels did not show significant difference between the groups. CONCLUSIONS: The effects of UF and furosemide therapies were similar on oxidative stress markers in patients with CRS. These methods safely decrease volume overload in a short-term period.
Description
WOS: 000406380900012
PubMed: 27097156
PubMed: 27097156
Keywords
Cardio, renal syndrome, Oxidative stress, Renal insufficiency, Ultrafiltration
Journal or Series
Minerva Urologica E Nefrologica
WoS Q Value
Q3
Scopus Q Value
N/A
Volume
69
Issue
4
