Mean Platelet Volume, Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Severe Preeclampsia

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dc.contributor.authorYavuzcan, Ali
dc.contributor.authorÇağlar, Mete
dc.contributor.authorÜstün, Yusuf
dc.contributor.authorDilbaz, Serdar
dc.contributor.authorÖzdemir, İsmail
dc.contributor.authorYıldız, Elif
dc.contributor.authorKumru, Selahattin
dc.date.accessioned2020-04-30T23:19:08Z
dc.date.available2020-04-30T23:19:08Z
dc.date.issued2014
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionKUMRU, Selahattin/0000-0001-6615-7666;en_US
dc.descriptionWOS: 000342327800006en_US
dc.descriptionPubMed: 24783431en_US
dc.description.abstractObjectives: The aim of the study was to compare the changes in the values of leukocytes, neutrophils, lymphocytes, mean platelet volume (MPV), and systemic inflammatory response (SIR) markers (neutrophil-lymphocyte ratio/platelet-lymphocyte ratio) in patients with severe preeclampsia (PE) of healthy pregnant and non-pregnant women. Material and methods: Hematological parameters including MPV and SIR markers [neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR)] were compered between the between three groups comprising of women with severe PE, healthy pregnant women and healthy non-pregnant women. Results: MPV and PLR did not show statistically significant differences between the three groups (p=0.081, p=0.098). NLR showed a statistically significant difference between the three groups (p=0.000). NLR values of patients with severe PE were statistically significantly higher than healthy non-pregnant women (p=0.000). No statistically significant difference was found between patients with severe PE and healthy pregnant women (p=0.721). The cut-off value of the leukocyte number for severe PE was 7.6 x 10(3)/ml, with 76.7% sensitivity and 60.6% specificity The cut-off value of neutrophil number was 6.4 x 10(3)/ml for the group with severe PE, with 76.7% sensitivity and 69% specificity. Conclusions: Our results showed that MPV level did not differ among patients with severe PE, healthy pregnant women and non-pregnant women. NLR cannot be used to identify patients with severe PE. PLR measured before termination of pregnancy is not an effective marker for severe PE, either.en_US
dc.identifier.endpage203en_US
dc.identifier.issn0017-0011
dc.identifier.issn2543-6767
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3658
dc.identifier.volume85en_US
dc.identifier.wosWOS:000342327800006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofGinekologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectleukocytesen_US
dc.subjectmean platelet volumeen_US
dc.subjectneutrophilsen_US
dc.subjectneutrophil-lymphocyte ratioen_US
dc.subjectplatelet-lymphocyte ratioen_US
dc.subjectpreeclampsiaen_US
dc.titleMean Platelet Volume, Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Severe Preeclampsiaen_US
dc.typeArticleen_US

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