The 2100 MHz radiofrequency radiation of a 3G-mobile phone and the DNA oxidative damage in brain

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dc.contributor.authorŞahin, Duygu
dc.contributor.authorÖzgür, Elçin
dc.contributor.authorGüler, Gülnur
dc.contributor.authorTomruk, Arın
dc.contributor.authorÜnlü, İlhan
dc.contributor.authorDinçel, Aylin Sepici
dc.contributor.authorSeyhan, Nesrin
dc.date.accessioned2020-04-30T23:32:37Z
dc.date.available2020-04-30T23:32:37Z
dc.date.issued2016
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionTomruk, Arin/0000-0002-7600-0811; Ozgur-Buyukatalay, Elcin/0000-0001-6428-918Xen_US
dc.descriptionWOS: 000381842500008en_US
dc.descriptionPubMed: 26775761en_US
dc.description.abstractWe aimed to evaluate the effect of 2100 MHz radiofrequency radiation emitted by a generator, simulating a 3G-mobile phone on the brain of rats during 10 and 40 days of exposure. The female rats were randomly divided into four groups. Group I; exposed to 3G modulated 2100 MHz RFR signal for 6 h/day, 5 consecutive days/wk for 2 weeks, group II; control 10 days, were kept in an inactive exposure set-up for 6 h/day, 5 consecutive days/wk for 2 weeks, group III; exposed to 3G modulated 2100 MHz RFR signal for 6 h/day, 5 consecutive days/wk for 8 weeks and group IV; control 40 days, were kept in an inactive exposure set-up for 6 h/day, 5 consecutive days/wk for 8 weeks. After the genomic DNA content of brain was extracted, oxidative DNA damage (8-hydroxy-2'deoxyguanosine, pg/mL) and malondialdehyde (MDA, nmoL/g tissue) levels were determined. Our main finding was the increased oxidative DNA damage to brain after 10 days of exposure with the decreased oxidative DNA damage following 40 days of exposure compared to their control groups. Besides decreased lipid peroxidation end product, MDA, was observed after 40 days of exposure. The measured decreased quantities of damage during the 40 days of exposure could be the means of adapted and increased DNA repair mechanisms. (C) 2016 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.jchemneu.2016.01.002en_US
dc.identifier.endpage98en_US
dc.identifier.issn0891-0618
dc.identifier.issn1873-6300
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage94en_US
dc.identifier.urihttps://doi.org/10.1016/j.jchemneu.2016.01.002
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4769
dc.identifier.volume75en_US
dc.identifier.wosWOS:000381842500008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofJournal Of Chemical Neuroanatomyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject2100MHz radiofrequency radiationen_US
dc.subjectMobile phone radiationen_US
dc.subjectBrainen_US
dc.subjectDNA oxidative damageen_US
dc.subjectLipid peroxidationen_US
dc.titleThe 2100 MHz radiofrequency radiation of a 3G-mobile phone and the DNA oxidative damage in brainen_US
dc.typeArticleen_US

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