Argyrophilic nucleolar organizing region associated protein synthesis in hair root cells of humans at different developmental stages and sex

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dc.contributor.authorEröz, Recep
dc.contributor.authorYılmaz, S.
dc.contributor.authorCücer, Nurhan
dc.date.accessioned2020-04-30T22:39:38Z
dc.date.available2020-04-30T22:39:38Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000321904800007en_US
dc.descriptionPubMed: 23480229en_US
dc.description.abstractArgyrophilic nucleolar organizing region (AgNORs) associated proteins are important for cell proliferation and various diseases. We investigated AgNOR protein synthesis in hair root cells of males and females at different ages using two-dimensional image analysis. Experiments were performed on 58 healthy male and 24 healthy female volunteers in three groups according to age and sex. Hair root cells obtained from hair follicles were stained with silver. Total AgNOR number/total nuclear number (TAN/TNN) and total AgNOR area/nuclear area (TAA/NA) for each nucleus were analyzed. The only significant difference was observed in TAA/NA values for males and females from 6 to 12 years old. We suggest that the difference is due to high NOR activity caused by increased growth hormone production in hair root cells.en_US
dc.identifier.doi10.3109/10520295.2013.769632en_US
dc.identifier.endpage271en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage267en_US
dc.identifier.urihttps://doi.org/10.3109/10520295.2013.769632
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2786
dc.identifier.volume88en_US
dc.identifier.wosWOS:000321904800007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnic & Histochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAgNORsen_US
dc.subjectdevelopmental stageen_US
dc.subjecthair rooten_US
dc.subjectrRNAen_US
dc.titleArgyrophilic nucleolar organizing region associated protein synthesis in hair root cells of humans at different developmental stages and sexen_US
dc.typeArticleen_US

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