Does topical ropivacaine reduce the posttonsillectomy morbidity in pediatric patients?

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dc.contributor.authorOğhan, Fatih
dc.contributor.authorHarputluoğlu, Uğur
dc.contributor.authorGüçlü, Ender
dc.contributor.authorKocaman, Buket
dc.contributor.authorÖztürk, Özcan
dc.date.accessioned2020-05-01T09:11:30Z
dc.date.available2020-05-01T09:11:30Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000253917800009en_US
dc.descriptionPubMed: 18179827en_US
dc.description.abstractObjectives: To determine whether post-operative administration of topical ropivacaine hydrochloride decreases morbidity following adenotonsillectomy. Study Design: Prospective, randomized, double-blind clinical trial. Setting: University referral center; ENT Department. Participants: Fourty one children, aged 4-16 years, undergoing tonsillectomy. Methods: Patients received 1.0% ropivacaine hydrochloride soaked swabs packed in their tonsillar fossae while the control group received saline-soaked swabs. Mc Grath's face scale was used to compare the two groups in respect of pain control. Chi-square and two-tailed unpaired Student's t-tests or Mann-Whitney-U-tests were used to compare the two independent groups. As 10 we made 11 comparision between groups, for Bonferroni correction, p < 0.005 was accepted as statistically significant. Results: Only first hour there was no significant pain-relieving effect seen in the ropivacaine group (p > 0.05). The other hours and days there were statistically significance between the two groups (p < 0.001). Also, the other post-operative parameters such as nausea, fever, vomiting, odor, bleeding, otalgia and trismus were not statistically different between the two groups. There were no complications associated with ropivacaine hydrochloride. No patients in this study suffered systemic side effects related to the use of this medication. Conclusion: Locally 1.0% ropivacaine administiration significantly relieves the pain of pediatric tonsillectomy and, it is a safe and effective method. High concentrations of ropivaciane may produce clinically significant pain relief. It is more effective to reduce of post-operative analgesic requirement after first hour. (c) 2007 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijporl.2007.11.011en_US
dc.identifier.endpage365en_US
dc.identifier.issn0165-5876
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage361en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijporl.2007.11.011
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5625
dc.identifier.volume72en_US
dc.identifier.wosWOS:000253917800009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Pediatric Otorhinolaryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectropivicaineen_US
dc.subjecttopical administrationen_US
dc.subjecttonsillectomyen_US
dc.subjectpainen_US
dc.titleDoes topical ropivacaine reduce the posttonsillectomy morbidity in pediatric patients?en_US
dc.typeArticleen_US

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