Vasoconstriction and analgesic efficacy of locally infiltrated levobupivacaine for nasal surgery

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dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorÖztürk, Özcan
dc.contributor.authorGüçlü, Ender
dc.contributor.authorİskender, Abdülkadir
dc.contributor.authorErgin, Mehmet Hakan
dc.contributor.authorTokmak, Abdurahman
dc.date.accessioned2020-04-30T23:46:54Z
dc.date.available2020-04-30T23:46:54Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000253393900050en_US
dc.descriptionPubMed: 18292454en_US
dc.description.abstractBACKGROUND: In this study, we compared the use of preincisional liclocaine 2% with epinephrine (LA) and levobupivacaine 0.25% plain (LB) for postoperative analgesia and vasoconstriction in patients undergoing nasal surgery. METHODS: Sixty patients were randomly assigned to receive preincisional local infiltration under general anesthesia. Group LB received levobupivacaine 0.25%, and group LA received epinephrine plus liclocaine 2% (add volume injected). Intraoperative hemodynamic changes, pre- and postoperative hemoglobin and hematocrit values were recorded. Visual analog scale values 30 min and 1, 2, 8, 12, and 24 h postoperatively and the need for rescue analgesic treatment in the first 24 h of all patients was recorded. RESULTS: At 30 min and 1, 2, 8, and 12 h postoperatively, visual analog scale values were lower in group LB than in group LA (P < 0.0001, P = 0.002, P = 0.023, P < 0.0001, and P = 0.011, respectively). The analgesic requirement was significantly lower in group LB when compared with that in group LA (P = 0.038). Group LB had significant differences between preoperative and postoperative hemoglobin and hematocrit values (P = 0.014 and 0.025). Group LA had significant differences between preoperative and postoperative hemoglobin and hematocrit values (P 0.031 and 0.024). CONCLUSIONS: We conclude that postoperative analgesia in nasal surgery with local infiltration of levobupivacaine was significantly more potent and longer lasting than that achieved by lidocaine plus epinephrine.en_US
dc.identifier.doi10.1213/ane.0b013e31816174c3en_US
dc.identifier.endpage1011en_US
dc.identifier.issn0003-2999
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1008en_US
dc.identifier.urihttps://doi.org/10.1213/ane.0b013e31816174c3
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5349
dc.identifier.volume106en_US
dc.identifier.wosWOS:000253393900050en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAnesthesia And Analgesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleVasoconstriction and analgesic efficacy of locally infiltrated levobupivacaine for nasal surgeryen_US
dc.typeArticleen_US

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