The effects of surgical repair on P-wave dispersion in children with secundum atrial septal defect

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dc.contributor.authorYavuz, Taner
dc.contributor.authorNişli, Kemal
dc.contributor.authorÖner, Naci
dc.contributor.authorDindar, Aygun
dc.contributor.authorAydoğan, Ümrah
dc.contributor.authorÖmeroğlu, Rukiye Eker
dc.contributor.authorErtuğrul, Türkan
dc.date.accessioned2020-04-30T23:33:31Z
dc.date.available2020-04-30T23:33:31Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000258652900006en_US
dc.descriptionPubMed: 18670742en_US
dc.description.abstractIntroduction: Atrial septal defect (ASD) is one of the most common congenital heart diseases in children. P-wave dispersion has been reported to be associated with non-homogeneous propagation of sinus impulses. The heterogeneity of atrial conduction time may predispose the atria to arrhythmias. The aim of this study was to determine the impact of surgical repair on P-wave indices in children with isolated secundum ASD. Methods: Children with isolated secundum ASD undergoing surgical repair (n=50; mean age, 7.0 +/- 3.0 years) and healthy controls (n=51; mean age, 7.6 +/- 2.7 years) were compared. Maximum P-wave duration (Pmax), shortest duration (Pmin) and P-wave dispersion (Pd) were measured using 12-lead surface electrocardiography. Results: Mean Pmax was found to be significantly higher in children with ASD compared with controls (95.2 +/- 10.8 vs 84.1 +/- 9.2 msec; P < 0.001), and Pd before surgery was significantly higher compared with controls (47.4 +/- 12.0 vs 38.8 +/- 9.7 msec; P < 0.001). Both P-wave indices were significantly decreased within the first year after surgical closure - the values decreased to those comparable to healthy controls (Pmax, 86.2 +/- 9.7 msec; Pd, 39.8 +/- 10.7 msec; P > 0.05). Conclusion: Surgical closure of ASD in children decreases Pmax and P-wave conduction time. We speculate that earlier closure of the defect may play an important role in avoiding permanent changes in the atrial myocardium and atrial fibrillation in adulthood.en_US
dc.identifier.doi10.1007/s12325-008-0081-3en_US
dc.identifier.endpage800en_US
dc.identifier.issn0741-238X
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage795en_US
dc.identifier.urihttps://doi.org/10.1007/s12325-008-0081-3
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4987
dc.identifier.volume25en_US
dc.identifier.wosWOS:000258652900006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAdvances In Therapyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectatrial septal defecten_US
dc.subjectchildrenen_US
dc.subjectelectrocardiographyen_US
dc.subjectP-wave dispersionen_US
dc.subjectsurgeryen_US
dc.titleThe effects of surgical repair on P-wave dispersion in children with secundum atrial septal defecten_US
dc.typeArticleen_US

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