The effects of surgical repair on P-wave dispersion in children with secundum atrial septal defect
Yükleniyor...
Dosyalar
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction: Atrial septal defect (ASD) is one of the most common congenital heart diseases in children. P-wave dispersion has been reported to be associated with non-homogeneous propagation of sinus impulses. The heterogeneity of atrial conduction time may predispose the atria to arrhythmias. The aim of this study was to determine the impact of surgical repair on P-wave indices in children with isolated secundum ASD. Methods: Children with isolated secundum ASD undergoing surgical repair (n=50; mean age, 7.0 +/- 3.0 years) and healthy controls (n=51; mean age, 7.6 +/- 2.7 years) were compared. Maximum P-wave duration (Pmax), shortest duration (Pmin) and P-wave dispersion (Pd) were measured using 12-lead surface electrocardiography. Results: Mean Pmax was found to be significantly higher in children with ASD compared with controls (95.2 +/- 10.8 vs 84.1 +/- 9.2 msec; P < 0.001), and Pd before surgery was significantly higher compared with controls (47.4 +/- 12.0 vs 38.8 +/- 9.7 msec; P < 0.001). Both P-wave indices were significantly decreased within the first year after surgical closure - the values decreased to those comparable to healthy controls (Pmax, 86.2 +/- 9.7 msec; Pd, 39.8 +/- 10.7 msec; P > 0.05). Conclusion: Surgical closure of ASD in children decreases Pmax and P-wave conduction time. We speculate that earlier closure of the defect may play an important role in avoiding permanent changes in the atrial myocardium and atrial fibrillation in adulthood.
Açıklama
WOS: 000258652900006
PubMed: 18670742
PubMed: 18670742
Anahtar Kelimeler
atrial septal defect, children, electrocardiography, P-wave dispersion, surgery
Kaynak
Advances In Therapy
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
25
Sayı
8
