Late-Onset BK Viruria in Renal Transplant Recipients

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dc.contributor.authorBoran, Mediha
dc.contributor.authorYıldırım, Tuğçe
dc.contributor.authorBoran, Ertay
dc.contributor.authorBoran, Mertay
dc.contributor.authorKılıç, H.
dc.date.accessioned2020-04-30T23:18:52Z
dc.date.available2020-04-30T23:18:52Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000360776700041en_US
dc.descriptionPubMed: 26293051en_US
dc.description.abstractBackground. Most cases of BK virus (BKV) infections emerge within the 1st years of kidney transplantation. We aimed to determine the prevalence of late-onset BKV infection and whether there are any differences between risk factors in early and late BKV infections. Methods. In this single-center retrospective study, we reviewed 300 kidney transplant recipients that were under regular follow-up and selected recipients with BKV infection and recorded associated risk factors, connection with immunosuppression, and responses to modification of treatment. Results. BKV was detected within the 1st 5 years after transplantation in 20 patients (6.6%, group 1) and after 5 years in 15 patients (5.0%, group 2). There were no significant differences between the 2 groups regarding age, sex, sex mismatches, donor type, BKV elimination time, serum creatinine, and estimated glomerular filtration rate at the times of BKV detection and last follow-up visit. In group 1, 2 recipients had biopsy-proven BKV-associated nephropathy (BKVAN), 3 recipients had BK viruria and viremia without BKVAN (biopsy proven), and 15 recipients (75%) had only BK viruria. In group 2, all of the patients had only BK viruria. In this group, on detection of BK viruria and immediate modification of immunosuppressive regimens prevented BK viremia. Conclusions. Routine screening of renal transplant recipients for BKV was indicated not only during the 1st 5 years, but also for the full follow-up period after transplantation.en_US
dc.identifier.doi10.1016/j.transproceed.2015.06.028en_US
dc.identifier.endpage1789en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1786en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2015.06.028
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3563
dc.identifier.volume47en_US
dc.identifier.wosWOS:000360776700041en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleLate-Onset BK Viruria in Renal Transplant Recipientsen_US
dc.typeArticleen_US

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