Pregnancy associated plasma protein-A and epilepsy
| dc.contributor.author | Coşkun, Abdurrahman | |
| dc.contributor.author | Özdemirli, Burcu | |
| dc.contributor.author | Memişoğulları, Ramazan | |
| dc.date.accessioned | 2020-04-30T23:21:26Z | |
| dc.date.available | 2020-04-30T23:21:26Z | |
| dc.date.issued | 2007 | |
| dc.department | DÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | en_US |
| dc.description | Coskun, Abdurrahman/0000-0002-1273-0604 | en_US |
| dc.description | WOS: 000254130800010 | en_US |
| dc.description.abstract | In this study, we aimed to investigate the role of pregnancy-associated plasma protein-A (PAPP-A) as insulin-like growth factor binding protein-4 (IGFBP-4) protease in epilepsy patients. We studied 16 epilepsy patients and 10 healthy controls. Serum PAPP-A levels of epilepsy patients (6.8 +/- 3.2 mU/L) were higher than of the control group (5.1 +/- 1.9 mU/L), but the difference was not statistically significant (P > 0.05). We concluded that PAPP-A may increase the bioavailability of insulin-like growth factors (IGFs) due to decreased neurogenesis and synthesis of IGFs in chronically epilepsy patients. | en_US |
| dc.identifier.endpage | 46 | en_US |
| dc.identifier.issn | 1300-0144 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopusquality | Q3 | en_US |
| dc.identifier.startpage | 45 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.12684/4193 | |
| dc.identifier.volume | 37 | en_US |
| dc.identifier.wosquality | N/A | en_US |
| dc.indekslendigikaynak | Web of Science | en_US |
| dc.indekslendigikaynak | Scopus | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Tubitak Scientific & Technical Research Council Turkey | en_US |
| dc.relation.ispartof | Turkish Journal Of Medical Sciences | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | brain tumor | en_US |
| dc.subject | epilepsy | en_US |
| dc.subject | IGF-I | en_US |
| dc.subject | IGFBP | en_US |
| dc.subject | ICFBP-4 | en_US |
| dc.subject | neurogenesis | en_US |
| dc.subject | PAPP-A | en_US |
| dc.title | Pregnancy associated plasma protein-A and epilepsy | en_US |
| dc.type | Article | en_US |
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